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Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

Karlsson Linnér, Richard and Biroli, Pietro and Kong, Edward and Meddens, S Fleur W and Wedow, Robbee and Fontana, Mark Alan and Lebreton, Maël and Tino, Stephen P and Abdellaoui, Abdel and Hammerschlag, Anke R and Nivard, Michel G and Okbay, Aysu and Rietveld, Cornelius A and Timshel, Pascal N and Trzaskowski, Maciej and Vlaming, Ronald de and Zünd, Christian L and Bao, Yanchun and Buzdugan, Laura and Caplin, Ann H and Chen, Chia-Yen and Eibich, Peter and Fontanillas, Pierre and Gonzalez, Juan R and Joshi, Peter K and Karhunen, Ville and Kleinman, Aaron and Levin, Remy Z and Lill, Christina M and Meddens, Gerardus A and Muntané, Gerard and Sanchez-Roige, Sandra and Rooij, Frank J van and Taskesen, Erdogan and Wu, Yang and Zhang, Futao and Auton, Adam and Boardman, Jason D and Clark, David W and Conlin, Andrew and Dolan, Conor C and Fischbacher, Urs and Groenen, Patrick JF and Harris, Kathleen Mullan and Hasler, Gregor and Hofman, Albert and Ikram, Mohammad A and Jain, Sonia and Karlsson, Robert and Kessler, Ronald C and Kooyman, Maarten and MacKillop, James and Männikkö, Minna and Morcillo-Suarez, Carlos and McQueen, Matthew B and Schmidt, Klaus M and Smart, Melissa C and Sutter, Matthias and Thurik, A Roy and Uitterlinden, André G and White, Jon and Wit, Harriet de and Yang, Jian and Bertram, Lars and Boomsma, Dorret I and Esko, Tõnu and Fehr, Ernst and Hinds, David A and Johannesson, Magnus and Kumari, Meena and Laibson, David and Magnusson, Patrik KE and Meyer, Michelle N and Navarro, Arcadi and Palmer, Abraham A and Pers, Tune H and Posthuma, Danielle and Schunk, Daniel and Stein, Murray B and Svento, Rauli and Tiemeier, Henning and Timmers, Paul RHJ and Turley, Patrick and Ursano, Robert J and Wagner, Gert G and Wilson, James F and Gratten, Jacob and Lee, James J and Cesarini, David and Benjamin, Daniel J and Koellinger, Philipp D and Beauchamp, Jonathan P (2019) Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences. Nature Genomics, 51 (2). pp. 245-257. DOI https://doi.org/10.1038/s41588-018-0309-3



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