Items where Author is "Schalkwyk, Leonard C"
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Flynn, Robert and Washer, Sam and Jeffries, Aaron R and Andrayas, Alexandria and Shireby, Gemma and Kumari, Meena and Schalkwyk, Leonard C and Mill, Jonathan and Hannon, Eilis (2022) Evaluation of nanopore sequencing for epigenetic epidemiology: a comparison with DNA methylation microarrays. Human Molecular Genetics, 31 (18). pp. 3181-3190. DOI https://doi.org/10.1093/hmg/ddac112
Wang, Yucheng and Gorrie-Stone, Tyler J and Grant, Olivia A and Andrayas, Alexandria D and Zhai, Xiaojun and McDonald-Maier, Klaus D and Schalkwyk, Leonard C (2022) InterpolatedXY: a two-step strategy to normalise DNA methylation microarray data avoiding sex bias. Bioinformatics, 38 (16). pp. 3950-3957. DOI https://doi.org/10.1093/bioinformatics/btac436
Min, Josine L and Hemani, Gibran and Hannon, Eilis and Dekkers, Koen F and Castillo-Fernandez, Juan and Luijk, René and Carnero-Montoro, Elena and Lawson, Daniel J and Burrows, Kimberley and Suderman, Matthew and Bretherick, Andrew D and Richardson, Tom G and Klughammer, Johanna and Iotchkova, Valentina and Sharp, Gemma and Al Khleifat, Ahmad and Shatunov, Aleksey and Iacoangeli, Alfredo and McArdle, Wendy L and Ho, Karen M and Kumar, Ashish and SöderhÀll, Cilla and Soriano-Tårraga, Carolina and Giralt-Steinhauer, Eva and Kazmi, Nabila and Mason, Dan and McRae, Allan F and Corcoran, David L and Sugden, Karen and Kasela, Silva and Cardona, Alexia and Day, Felix R and Cugliari, Giovanni and Viberti, Clara and Guarrera, Simonetta and Lerro, Michael and Gupta, Richa and Bollepalli, Sailalitha and Mandaviya, Pooja and Zeng, Yanni and Clarke, Toni-Kim and Walker, Rosie M and Schmoll, Vanessa and Czamara, Darina and Ruiz-Arenas, Carlos and Rezwan, Faisal I and Marioni, Riccardo E and Lin, Tian and Awaloff, Yvonne and Germain, Marine and Aïssi, Dylan and Zwamborn, Ramona and van Eijk, Kristel and Dekker, Annelot and van Dongen, Jenny and Hottenga, Jouke-Jan and Willemsen, Gonneke and Xu, Cheng-Jian and Barturen, Guillermo and Català -Moll, Francesc and Kerick, Martin and Wang, Carol and Melton, Phillip and Elliott, Hannah R and Shin, Jean and Bernard, Manon and Yet, Idil and Smart, Melissa and Gorrie-Stone, Tyler and Shaw, Chris and Al Chalabi, Ammar and Ring, Susan M and Pershagen, Göran and Melén, Erik and Jiménez-Conde, Jordi and Roquer, Jaume and Lawlor, Deborah A and Wright, John and Martin, Nicholas G and Montgomery, Grant W and Moffitt, Terrie E and Poulton, Richie and Esko, TÔnu and Milani, Lili and Metspalu, Andres and Perry, John RB and Ong, Ken K and Wareham, Nicholas J and Matullo, Giuseppe and Sacerdote, Carlotta and Panico, Salvatore and Caspi, Avshalom and Arseneault, Louise and Gagnon, France and Ollikainen, Miina and Kaprio, Jaakko and Felix, Janine F and Rivadeneira, Fernando and Tiemeier, Henning and van IJzendoorn, Marinus H and Uitterlinden, André G and Jaddoe, Vincent WV and Haley, Chris and McIntosh, Andrew M and Evans, Kathryn L and Murray, Alison and RÀikkönen, Katri and Lahti, Jari and Nohr, Ellen A and SÞrensen, Thorkild IA and Hansen, Torben and Morgen, Camilla S and Binder, Elisabeth B and Lucae, Susanne and Gonzalez, Juan Ramon and Bustamante, Mariona and Sunyer, Jordi and Holloway, John W and Karmaus, Wilfried and Zhang, Hongmei and Deary, Ian J and Wray, Naomi R and Starr, John M and Beekman, Marian and van Heemst, Diana and Slagboom, P Eline and Morange, Pierre-Emmanuel and Trégouët, David-Alexandre and Veldink, Jan H and Davies, Gareth E and de Geus, Eco JC and Boomsma, Dorret I and Vonk, Judith M and Brunekreef, Bert and Koppelman, Gerard H and Alarcón-Riquelme, Marta E and Huang, Rae-Chi and Pennell, Craig E and van Meurs, Joyce and Ikram, M Arfan and Hughes, Alun D and Tillin, Therese and Chaturvedi, Nish and Pausova, Zdenka and Paus, Tomas and Spector, Timothy D and Kumari, Meena and Schalkwyk, Leonard C and Visscher, Peter M and Davey Smith, George and Bock, Christoph and Gaunt, Tom R and Bell, Jordana T and Heijmans, Bastiaan T and Mill, Jonathan and Relton, Caroline L (2021) Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation. Nature Genetics, 53 (9). pp. 1311-1321. DOI https://doi.org/10.1038/s41588-021-00923-x
Shireby, Gemma L and Davies, Jonathan P and Francis, Paul T and Burrage, Joe and Walker, Emma M and Neilson, Grant WA and Dahir, Aisha and Thomas, Alan J and Love, Seth and Smith, Rebecca G and Lunnon, Katie and Kumari, Meena and Schalkwyk, Leonard C and Morgan, Kevin and Brookes, Keeley and Hannon, Eilis and Mill, Jonathan (2020) Recalibrating the epigenetic clock: implications for assessing biological age in the human cortex. Brain: a journal of neurology, 143 (12). pp. 3763-3775. DOI https://doi.org/10.1093/brain/awaa334
Ă senius, Fredrika and Gorrie-Stone, Tyler J and Brew, Ama and Panchbhaya, Yasmin and Williamson, Elizabeth and Schalkwyk, Leonard C and Rakyan, Vardhman K and Holland, Michelle L and Marzi, Sarah J and Williams, David J (2020) The DNA methylome of human sperm is distinct from blood with little evidence for tissue-consistent obesity associations. PLoS Genetics, 16 (10). e1009035-e1009035. DOI https://doi.org/10.1371/journal.pgen.1009035
Bell, Christopher G and Lowe, Robert and Adams, Peter D and Baccarelli, Andrea A and Beck, Stephan and Bell, Jordana T and Christensen, Brock C and Gladyshev, Vadim N and Heijmans, Bastiaan T and Horvath, Steve and Ideker, Trey and Issa, Jean-Pierre J and Kelsey, Karl T and Marioni, Riccardo E and Reik, Wolf and Relton, Caroline L and Schalkwyk, Leonard C and Teschendorff, Andrew E and Wagner, Wolfgang and Zhang, Kang and Rakyan, Vardhman K (2019) DNA methylation aging clocks: challenges and recommendations. Genome Biology, 20 (1). 249-. DOI https://doi.org/10.1186/s13059-019-1824-y
Saffari, Ayden and Arno, Matt and Nasser, Eric and Ronald, Angelica and Wong, Chloe CY and Schalkwyk, Leonard C and Mill, Jonathan and Dudbridge, Frank and Meaburn, Emma L (2019) RNA sequencing of identical twins discordant for autism reveals blood-based signatures implicating immune and transcriptional dysregulation. Molecular Autism, 10 (1). p. 38. DOI https://doi.org/10.1186/s13229-019-0285-1
OâBrien, Heath E and Hannon, Eilis and Hill, Matthew J and Toste, Carolina C and Robertson, Matthew J and Morgan, Joanne E and McLaughlin, Gemma and Lewis, Cathryn M and Schalkwyk, Leonard C and Hall, Lynsey S and Pardiñas, Antonio F and Owen, Michael J and OâDonovan, Michael C and Mill, Jonathan and Bray, Nicholas J (2018) Expression quantitative trait loci in the developing human brain and their enrichment in neuropsychiatric disorders. Genome Biology, 19 (1). 194-. DOI https://doi.org/10.1186/s13059-018-1567-1
Hannon, Ellis and Gorrie-Stone, Tyler J and Smart, Melissa C and Burrage, Joe and Hughes, Amanda and Bao, Yanchun and Kumari, Meena and Schalkwyk, Leonard C and Mill, Jonathan (2018) Leveraging DNA-Methylation Quantitative-Trait Loci to Characterize the Relationship between Methylomic Variation, Gene Expression, and Complex Traits. The American Journal of Human Genetics, 103 (5). pp. 654-665. DOI https://doi.org/10.1016/j.ajhg.2018.09.007
Marzi, Sarah J and Leung, Szi Kay and Ribarska, Teodora and Hannon, Eilis and Smith, Adam R and Pishva, Ehsan and Poschmann, Jeremie and Moore, Karen and Troakes, Claire and Al-Sarraj, Safa and Beck, Stephan and Newman, Stuart and Lunnon, Katie and Schalkwyk, Leonard C and Mill, Jonathan (2018) A histone acetylome-wide association study of Alzheimerâs disease identifies disease-associated H3K27ac differences in the entorhinal cortex. Nature Neuroscience, 21 (11). pp. 1618-1627. DOI https://doi.org/10.1038/s41593-018-0253-7
Janecka, Magdalena and Haworth, Claire MA and Ronald, Angelica and Krapohl, Eva and HappĂ©, Francesca and Mill, Jonathan and Schalkwyk, Leonard C and Fernandes, Cathy and Reichenberg, Abraham and Rijsdijk, FrĂŒhling (2017) Paternal Age Alters Social Development in Offspring. Journal of the American Academy of Child & Adolescent Psychiatry, 56 (5). pp. 383-390. DOI https://doi.org/10.1016/j.jaac.2017.02.006
Malki, Karim and Tosto, Maria Grazia and MouriñoâTalĂn, HĂ©ctor and RodrĂguezâLorenzo, Sabela and Pain, Oliver and Jumhaboy, Irfan and Liu, Tina and Parpas, Panos and Newman, Stuart and Malykh, Artem and Carboni, Lucia and Uher, Rudolf and McGuffin, Peter and Schalkwyk, Leonard C and Bryson, Kevin and Herbster, Mark (2017) Highly polygenic architecture of antidepressant treatment response: Comparative analysis of SSRI and NRI treatment in an animal model of depression. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 174 (3). pp. 235-250. DOI https://doi.org/10.1002/ajmg.b.32494
Malki, Karim and Du Rietz, Ebba and Crusio, Wim E and Pain, Oliver and PayaâCano, Jose and Karadaghi, Rezhaw L and Sluyter, Frans and de Boer, Sietse F and Sandnabba, Kenneth and Schalkwyk, Leonard C and Asherson, Philip and Tosto, Maria Grazia (2016) Transcriptome analysis of genes and gene networks involved in aggressive behavior in mouse and zebrafish. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 171 (6). pp. 827-838. DOI https://doi.org/10.1002/ajmg.b.32451
Marzi, Sarah J and Meaburn, Emma L and Dempster, Emma L and Lunnon, Katie and Paya-Cano, Jose L and Smith, Rebecca G and Volta, Manuela and Troakes, Claire and Schalkwyk, Leonard C and Mill, Jonathan (2016) Tissue-specific patterns of allelically-skewed DNA methylation. Epigenetics, 11 (1). pp. 24-35. DOI https://doi.org/10.1080/15592294.2015.1127479
Hannon, Eilis and Spiers, Helen and Viana, Joana and Pidsley, Ruth and Burrage, Joe and Murphy, Therese M and Troakes, Claire and Turecki, Gustavo and O'Donovan, Michael C and Schalkwyk, Leonard C and Bray, Nicholas J and Mill, Jonathan (2016) Methylation QTLs in the developing brain and their enrichment in schizophrenia risk loci. Nature Neuroscience, 19 (1). pp. 48-54. DOI https://doi.org/10.1038/nn.4182
Malki, Karim and Mineur, Yann S and Tosto, Maria Grazia and Campbell, James and Karia, Priya and Jumabhoy, Irfan and Sluyter, Frans and Crusio, Wim E and Schalkwyk, Leonard C (2015) Pervasive and opposing effects of Unpredictable Chronic Mild Stress (UCMS) on hippocampal gene expression in BALB/cJ and C57BL/6J mouse strains. BMC Genomics, 16 (1). 262-. DOI https://doi.org/10.1186/s12864-015-1431-6
Spiers, Helen and Hannon, Eilis and Schalkwyk, Leonard C and Smith, Rebecca and Wong, Chloe CY and OâDonovan, Michael C and Bray, Nicholas J and Mill, Jonathan (2015) Methylomic trajectories across human fetal brain development. Genome Research, 25 (3). pp. 338-352. DOI https://doi.org/10.1101/gr.180273.114
Martin, Charlotte and Tansey, Katherine E and Schalkwyk, Leonard C and Powell, Timothy R (2015) The inflammatory cytokines: molecular biomarkers for major depressive disorder? Biomarkers in Medicine, 9 (2). pp. 169-180. DOI https://doi.org/10.2217/bmm.14.29
Boks, Marco P and Mierlo, Hans C van and Rutten, Bart PF and Radstake, Timothy RDJ and De Witte, Lot and Geuze, Elbert and Horvath, Steve and Schalkwyk, Leonard C and Vinkers, Christiaan H and Broen, Jasper CA and Vermetten, Eric (2015) Longitudinal changes of telomere length and epigenetic age related to traumatic stress and post-traumatic stress disorder. Psychoneuroendocrinology, 51. pp. 506-512. DOI https://doi.org/10.1016/j.psyneuen.2014.07.011
Malki, Karim and Pain, Oliver and Du Rietz, Ebba and Tosto, Maria Grazia and Paya-Cano, Jose and Sandnabba, Kenneth N and de Boer, Sietse and Schalkwyk, Leonard C and Sluyter, Frans (2014) Genes and Gene Networks Implicated in Aggression Related Behaviour. neurogenetics, 15 (4). pp. 255-266. DOI https://doi.org/10.1007/s10048-014-0417-x
De Jager, Philip L and Srivastava, Gyan and Lunnon, Katie and Burgess, Jeremy and Schalkwyk, Leonard C and Yu, Lei and Eaton, Matthew L and Keenan, Brendan T and Ernst, Jason and McCabe, Cristin and Tang, Anna and Raj, Towfique and Replogle, Joseph and Brodeur, Wendy and Gabriel, Stacey and Chai, High S and Younkin, Curtis and Younkin, Steven G and Zou, Fanggeng and Szyf, Moshe and Epstein, Charles B and Schneider, Julie A and Bernstein, Bradley E and Meissner, Alex and Ertekin-Taner, Nilufer and Chibnik, Lori B and Kellis, Manolis and Mill, Jonathan and Bennett, David A (2014) Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci. Nature Neuroscience, 17 (9). pp. 1156-1163. DOI https://doi.org/10.1038/nn.3786
Lunnon, Katie and Smith, Rebecca and Hannon, Eilis and De Jager, Philip L and Srivastava, Gyan and Volta, Manuela and Troakes, Claire and Al-Sarraj, Safa and Burrage, Joe and Macdonald, Ruby and Condliffe, Daniel and Harries, Lorna W and Katsel, Pavel and Haroutunian, Vahram and Kaminsky, Zachary and Joachim, Catharine and Powell, John and Lovestone, Simon and Bennett, David A and Schalkwyk, Leonard C and Mill, Jonathan (2014) Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease. Nature Neuroscience, 17 (9). pp. 1164-1170. DOI https://doi.org/10.1038/nn.3782
Powell, Timothy R and PowellâSmith, Georgia and Haddley, Kate and Mcguffin, Peter and Quinn, John and Schalkwyk, Leonard C and Farmer, Anne E and D'Souza, Ursula M (2014) Moodâstabilizers differentially affect housekeeping gene expression in human cells. International Journal of Methods in Psychiatric Research, 23 (2). pp. 279-288. DOI https://doi.org/10.1002/mpr.1435
Tarantino, Lisa M and Schalkwyk, Leonard C (2014) Introduction to mammalian genome special issue: genetics of behavior. Mammalian Genome, 25 (1-2). pp. 1-2. DOI https://doi.org/10.1007/s00335-013-9496-5
Malki, Karim and Tosto, Maria Grazia and Jumabhoy, Irfan and Lourdusamy, Anbarasu and Sluyter, Frans and Craig, Ian and Uher, Rudolf and McGuffin, Peter and Schalkwyk, Leonard C (2013) Integrative mouse and human mRNA studies using WGCNA nominates novel candidate genes involved in the pathogenesis of major depressive disorder. Pharmacogenomics, 14 (16). pp. 1979-1990. DOI https://doi.org/10.2217/pgs.13.154
Powell, Timothy R and Schalkwyk, Leonard C and Heffernan, Andrew L and Breen, Gerome and Lawrence, Timothy and Price, Tom and Farmer, Anne E and Aitchison, Katherine J and Craig, Ian W and Danese, Andrea and Lewis, Cathryn and McGuffin, Peter and Uher, Rudolf and Tansey, Katherine E and D'Souza, Ursula M (2013) Tumor necrosis factor and its targets in the inflammatory cytokine pathway are identified as putative transcriptomic biomarkers for escitalopram response. European Neuropsychopharmacology, 23 (9). pp. 1105-1114. DOI https://doi.org/10.1016/j.euroneuro.2012.09.009
Powell, Timothy R and Tansey, Katherine E and Breen, Gerome and Farmer, Anne E and Craig, Ian W and Uher, Rudolf and McGuffin, Peter and DâSouza, Ursula M and Schalkwyk, Leonard C (2013) ATP-binding cassette sub-family F member 1 (ABCF1) is identified as a putative therapeutic target of escitalopram in the inflammatory cytokine pathway. Journal of Psychopharmacology, 27 (7). pp. 609-615. DOI https://doi.org/10.1177/0269881113490329
Malki, Karim and Lourdusamy, Anbarasu and Binder, Elke and PayĂĄ-Cano, Jose and Sluyter, Frans and Craig, Ian and Keers, Robert and McGuffin, Peter and Uher, Rudolf and Schalkwyk, Leonard C (2012) Antidepressant-dependent mRNA changes in mouse associated with hippocampal neurogenesis in a mouse model of depression. Pharmacogenetics and Genomics, 22 (11). pp. 765-776. DOI https://doi.org/10.1097/fpc.0b013e328356fa90
Jeffries, Aaron R and Perfect, Leo W and Ledderose, Julia and Schalkwyk, Leonard C and Bray, Nicholas J and Mill, Jonathan and Price, Jack (2012) Stochastic Choice of Allelic Expression in Human Neural Stem Cells. Stem Cells, 30 (9). pp. 1938-1947. DOI https://doi.org/10.1002/stem.1155
Malki, Karim and Campbell, James and Davies, Matthew and Keers, Robert and Uher, Rudolf and Ward, Malcolm and PayaâCano, Jose and Aitchinson, Katherine J and Binder, Elke and Sluyter, Frans and Kuhn, Karsten and Selzer, Stefan and Craig, Ian and McGuffin, Peter and Schalkwyk, Leonard C (2012) Pharmacoproteomic investigation into antidepressant response in two mouse inbred strains. PROTEOMICS, 12 (14). pp. 2355-2365. DOI https://doi.org/10.1002/pmic.201100306
Dempster, Emma L and Pidsley, Ruth and Schalkwyk, Leonard C and Owens, Sheena and Georgiades, Anna and Kane, Fergus and Kalidindi, Sridevi and Picchioni, Marco and Kravariti, Eugenia and Toulopoulou, Timothea and Murray, Robin M and Mill, Jonathan (2011) Disease-associated epigenetic changes in monozygotic twins discordant for schizophrenia and bipolar disorder. Human Molecular Genetics, 20 (24). pp. 4786-4796. DOI https://doi.org/10.1093/hmg/ddr416
Binder, Elke and Malki, Karim and Paya-Cano, Jose L and Fernandes, Cathy and Aitchison, Katherine J and Mathé, Aleksander A and Sluyter, Frans and Schalkwyk, Leonard C (2011) Antidepressants and the resilience to early-life stress in inbred mouse strains. Pharmacogenetics and Genomics, 21 (12). pp. 779-789. DOI https://doi.org/10.1097/fpc.0b013e32834b3f35
KÔks, Sulev and Soomets, Ursel and Plaas, Mario and Terasmaa, Anton and Noormets, Klari and Tillmann, Vallo and Vasar, Eero and Fernandes, Cathy and Schalkwyk, Leonard C (2011) Hypothalamic gene expression profile indicates a reduction in G protein signaling in the <i>Wfs1</i> mutant mice. Physiological Genomics, 43 (24). pp. 1351-1358. DOI https://doi.org/10.1152/physiolgenomics.00117.2011
Malki, Karim and Uher, Rudolf and Paya-Cano, Jose and Binder, Elke and Rietschel, Marcella and Zobel, Astrid and Mors, Ole and Hauser, Joanna and Henigsberg, Neven and Jerman, Borut and Souery, Daniel and Placentino, Anna and Ng, Mandy Y and Cohen-Woods, Sarah and Sluyter, Frans and Farmer, Anne and Aitchison, Katherine J and Craig, Ian W and Lewis, Cathryn M and McGuffin, Peter and Schalkwyk, Leonard C (2011) Convergent Animal and Human Evidence Suggests a Role of PPM1A Gene in Response to Antidepressants. Biological Psychiatry, 69 (4). pp. 360-365. DOI https://doi.org/10.1016/j.biopsych.2010.08.011
Davis, Oliver SP and Butcher, Lee M and Docherty, Sophia J and Meaburn, Emma L and Curtis, Charles JC and Simpson, Michael A and Schalkwyk, Leonard C and Plomin, Robert (2010) A Three-Stage Genome-Wide Association Study of General Cognitive Ability: Hunting the Small Effects. Behavior Genetics, 40 (6). pp. 759-767. DOI https://doi.org/10.1007/s10519-010-9350-4
Meaburn, Emma L and Schalkwyk, Leonard C and Mill, Jonathan (2010) Allele-specific methylation in the human genome. Epigenetics, 5 (7). pp. 578-582. DOI https://doi.org/10.4161/epi.5.7.12960
Schalkwyk, Leonard C and Meaburn, Emma L and Smith, Rebecca and Dempster, Emma L and Jeffries, Aaron R and Davies, Matthew N and Plomin, Robert and Mill, Jonathan (2010) Allelic Skewing of DNA Methylation Is Widespread across the Genome. The American Journal of Human Genetics, 86 (2). pp. 196-212. DOI https://doi.org/10.1016/j.ajhg.2010.01.014
Ronald, Angelica and Butcher, Lee M and Docherty, Sophia and Davis, Oliver SP and Schalkwyk, Leonard C and Craig, Ian W and Plomin, Robert (2010) A Genome-Wide Association Study of Social and Non-Social Autistic-Like Traits in the General Population Using Pooled DNA, 500Â K SNP Microarrays and Both Community and Diagnosed Autism Replication Samples. Behavior Genetics, 40 (1). pp. 31-45. DOI https://doi.org/10.1007/s10519-009-9308-6
Ronald, Angelica and Butcher, Lee M and Docherty, Sophia J and Davis, Oliver SP and Schalkwyk, Leonard C and Craig, Ian W and Plomin, Robert (2010) Response to comment by Stuart Macgregor. Behavior Genetics, 40 (1). p. 48. DOI https://doi.org/10.1007/s10519-009-9319-3
Smith, Rebecca G and Kember, Rachel L and Mill, Jonathan and Fernandes, Cathy and Schalkwyk, Leonard C and Buxbaum, Joseph D and Reichenberg, Abraham (2009) Advancing Paternal Age Is Associated with Deficits in Social and Exploratory Behaviors in the Offspring: A Mouse Model. PLoS ONE, 4 (12). e8456-e8456. DOI https://doi.org/10.1371/journal.pone.0008456
Davies, Matthew N and Lawn, Sarah and Whatley, Steven and Fernandes, Cathy and Williams, Robert W and Schalkwyk, Leonard C (2009) To What Extent is Blood a Reasonable Surrogate for Brain in Gene Expression Studies: Estimation from Mouse Hippocampus and Spleen. Frontiers in Neuroscience, 3 (OCT). 54-. DOI https://doi.org/10.3389/neuro.15.002.2009
Davis, Oliver SP and Plomin, Robert and Schalkwyk, Leonard C (2009) The SNPMaP package for R: a framework for genome-wide association using DNA pooling on microarrays. Bioinformatics, 25 (2). pp. 281-283. DOI https://doi.org/10.1093/bioinformatics/btn587
Parsons, Michael J and Grimm, Christina H and Paya-Cano, Jose L and Sugden, Karen and Nietfeld, Wilfried and Lehrach, Hans and Schalkwyk, Leonard C (2008) Using hippocampal microRNA expression differences between mouse inbred strains to characterise miRNA function. Mammalian Genome, 19 (7-8). pp. 552-560. DOI https://doi.org/10.1007/s00335-008-9116-y
KÔks, Sulev and Fernandes, Cathy and Kurrikoff, Kaido and Vasar, Eero and Schalkwyk, Leonard C (2008) Gene expression profiling reveals upregulation of Tlr4 receptors in Cckb receptor deficient mice. Behavioural Brain Research, 188 (1). pp. 62-70. DOI https://doi.org/10.1016/j.bbr.2007.10.020
Caspi, Avshalom and Williams, Benjamin and Kim-Cohen, Julia and Craig, Ian W and Milne, Barry J and Poulton, Richie and Schalkwyk, Leonard C and Taylor, Alan and Werts, Helen and Moffitt, Terrie E (2007) Moderation of breastfeeding effects on the IQ by genetic variation in fatty acid metabolism. Proceedings of the National Academy of Sciences, 104 (47). pp. 18860-18865. DOI https://doi.org/10.1073/pnas.0704292104
Meaburn, Emma and Harlaar, Nicole and Craig, Ian W and Schalkwyk, Leonard C and Plomin, Robert (2007) Genomewide gene expression profiles as a biological basis for non-shared environment: MZ twins discordant for reading ability. In: UNSPECIFIED, ? - ?.
Lad, Heena V and Liu, Lin and Payå-Cano, José L and Fernandes, Cathy and Schalkwyk, Leonard C (2007) Quantitative traits for the tail suspension test: automation, optimization, and BXD RI mapping. Mammalian Genome, 18 (6-7). pp. 482-491. DOI https://doi.org/10.1007/s00335-007-9029-1
Plomin, Robert and Schalkwyk, Leonard C (2007) Microarrays. Developmental Science, 10 (1). pp. 19-23. DOI https://doi.org/10.1111/j.1467-7687.2007.00558.x
Meaburn, Emma and Butcher, Lee M and Harlaar, Nicole and Curtis, Charles and Craig, Ian W and Schalkwyk, Leonard C and Plomin, Robert (2006) An association scan using pooled DNA and 100k SNPS identifies a 'SNP set' for early reading. In: UNSPECIFIED, ? - ?.
Galsworthy, Michael J and Paya-Cano, Jose L and Liu, Lin and MonleĂłn, Santiago and Gregoryan, Gregory and Fernandes, Cathy and Schalkwyk, Leonard C and Plomin, Robert (2005) Assessing Reliability, Heritability and General Cognitive Ability in a Battery of Cognitive Tasks for Laboratory Mice. Behavior Genetics, 35 (5). pp. 675-692. DOI https://doi.org/10.1007/s10519-005-3423-9
Butcher, Lee M and Meaburn, Emma and Knight, Jo and Sham, Pak C and Schalkwyk, Leonard C and Craig, Ian W and Plomin, Robert (2005) SNPs, microarrays and pooled DNA: identification of four loci associated with mild mental impairment in a sample of 6000 children. Human Molecular Genetics, 14 (10). pp. 1315-1325. DOI https://doi.org/10.1093/hmg/ddi142
Fernandes, Cathy and Liu, Lin and Paya-Cano, Jos L and Gregorovïżœ, So A and Forejt, Ji and Schalkwyk, Leonard C (2004) Behavioral Characterization of Wild Derived Male Mice (Mus musculus musculus) of the PWD/Ph Inbred Strain: High Exploration Compared to C57BL/6J. Behavior Genetics, 34 (6). pp. 621-630. DOI https://doi.org/10.1007/s10519-004-5589-y
Craig, Ian W and Mill, Jonathan and Craig, Gavin M and Loat, Caroline and Schalkwyk, Leonard C (2004) Application of microarrays to the analysis of the inactivation status of human X-linked genes expressed in lymphocytes. European Journal of Human Genetics, 12 (8). pp. 639-646. DOI https://doi.org/10.1038/sj.ejhg.5201212
Ben Abdelkhalek, Hanaa and Beckers, Anja and Schuster-Gossler, Karin and Pavlova, Maria N and Burkhardt, Hannelore and Lickert, Heiko and Rossant, Janet and Reinhardt, Richard and Schalkwyk, Leonard C and MĂŒller, Ines and Herrmann, Bernhard G and Ceolin, Marcelo and Rivera-Pomar, Rolando and Gossler, Achim (2004) The mouse homeobox gene <i>Not</i> is required for caudal notochord development and affected by the truncate mutation. Genes & Development, 18 (14). pp. 1725-1736. DOI https://doi.org/10.1101/gad.303504
Fernandes, Cathy and PayaâCano, Jose L and Sluyter, Frans and D'Souza, Ursula and Plomin, Robert and Schalkwyk, Leonard C (2004) Hippocampal gene expression profiling across eight mouse inbred strains: towards understanding the molecular basis for behaviour. European Journal of Neuroscience, 19 (9). pp. 2576-2582. DOI https://doi.org/10.1111/j.0953-816x.2004.03358.x
Sluyter, Frans and Schalkwyk, Leonard C (2003) Aggression across species. Behavior Genetics, 33 (5). pp. 457-460. DOI https://doi.org/10.1023/a:1025744430180
Klose, Joachim and Nock, Christina and Herrmann, Marion and StĂŒhler, Kai and Marcus, Katrin and BlĂŒggel, Martin and Krause, Eberhard and Schalkwyk, Leonard C and Rastan, Sohaila and Brown, Steve DM and BĂŒssow, Konrad and Himmelbauer, Heinz and Lehrach, Hans (2002) Genetic analysis of the mouse brain proteome. Nature Genetics, 30 (4). pp. 385-393. DOI https://doi.org/10.1038/ng861
Schalkwyk, Leonard C and Cusack, Brian and Dunkel, Ilona and Hopp, Martina and Kramer, Markus and Palczewski, Stefanie and Piefke, Jutta and Scheel, Sabine and Weiher, Michael and Wenske, Gunther and Lehrach, Hans and Himmelbauer, Heinz (2001) Advanced Integrated Mouse YAC Map Including BAC Framework. Genome Research, 11 (12). pp. 2142-2150. DOI https://doi.org/10.1101/gr.176201
Gösele, Claudia and Hong, Liu and Kreitler, Thomas and Rossmann, Marlies and Hieke, Brigitte and GroĂ, Uwe and Kramer, Markus and Himmelbauer, Heinz and Bihoreau, Marie-ThĂ©rese and Kwitek-Black, Anne E and Twigger, Simon and Tonellato, Peter J and Jacob, Howard J and Schalkwyk, Leonard C and Lindpaintner, Klaus and Ganten, Detlev and Lehrach, Hans and Knoblauch, Margit (2000) High-Throughput Scanning of the Rat Genome Using Interspersed Repetitive Sequence-PCR Markers. Genomics, 69 (3). pp. 287-294. DOI https://doi.org/10.1006/geno.2000.6352
Leong, Wey L and Dobson, Melanie J and Logsdon, Jr., John M and Abdel-Majid, Raja M and Schalkwyk, Leonard C and Guernsey, Duane L and Neumann, Paul E (2000) ETn insertion in the mouse Adcy1 gene: transcriptional and phylogenetic analyses. Mammalian Genome, 11 (2). pp. 97-103. DOI https://doi.org/10.1007/s003350010020
Schalkwyk, Leonard C and Jung, Martin and Daser, Angelika and Weiher, Michael and Walter, Jörn and Himmelbauer, Heinz and Lehrach, Hans (1999) Panel of Microsatellite Markers for Whole-Genome Scans and Radiation Hybrid Mapping and a Mouse Family Tree. Genome Research, 9 (9). pp. 878-887. DOI https://doi.org/10.1101/gr.9.9.878
Hills, David and Tracey, Simon and Masabanda, Julio and Fries, Ruedi and Schalkwyk, Leonard C and Lehrach, Hans and Miller, J Ross and Williams, John L (1999) A bovine YAC library containing four- to five-fold genome equivalents. Mammalian Genome, 10 (8). pp. 837-838. DOI https://doi.org/10.1007/s003359901100
Zhu, Baoli and Smith, Judith A and Tracey, Simon M and Konfortov, Bernard A and Welzel, Katrin and Schalkwyk, Leonard C and Lehrach, Hans and Kollers, Sonja and Masabanda, Julio and Buitkamp, Johannes and Fries, Ruedi and Williams, John L and Miller, J Ross (1999) A 5Ă genome coverage bovine BAC library: production, characterization, and distribution. Mammalian Genome, 10 (7). pp. 706-709. DOI https://doi.org/10.1007/s003359901075
Nock, Christina and Gauss, Christine and Schalkwyk, Leonard C and Klose, Joachim and Lehrach, Hans and Himmelbauer, Heinz (1999) Technology development at the interface of proteome research and genomics: Mapping nonpolymorphic proteins on the physical map of mouse chromosomes. Electrophoresis, 20 (4-5). pp. 1027-1032. DOI https://doi.org/10.1002/(sici)1522-2683(19990101)20:4/5<1027::aid-elps1027>3.0.co;2-i
Schalkwyk, Leonard C and Weiher, Michael and Kirby, Michelle and Cusack, Brian and Himmelbauer, Heinz and Lehrach, Hans (1998) Refined radiation hybrid map of mouse Chromosome 17. Mammalian Genome, 9 (10). pp. 807-811. DOI https://doi.org/10.1007/s003359900871
Abdel-Majid, Raja M and Leong, Wey L and Schalkwyk, Leonard C and Smallman, Donald S and Wong, Scott T and Storm, Daniel R and Fine, Alan and Dobson, Melanie J and Guernsey, Duane L and Neumann, Paul E (1998) Loss of adenylyl cyclase I activity disrupts patterning of mouse somatosensory cortex. Nature Genetics, 19 (3). pp. 289-291. DOI https://doi.org/10.1038/980
Himmelbauer, Heinz and Wedemeyer, Niels and Haaf, Thomas and Wanker, Erich E and Schalkwyk, Leonard C and Lehrach, Hans (1998) IRS-PCR-based genetic mapping of the huntingtin interacting protein gene (HIP1) on mouse Chromosome 5. Mammalian Genome, 9 (1). pp. 26-31. DOI https://doi.org/10.1007/s003359900674
Cai, Li and Schalkwyk, Leonard C and Schoeberlein-Stehli, Andreina and Zee, Robert YL and Smith, Avrial and Haaf, Thomas and Georges, Michel and Lehrach, Hans and Lindpaintner, Klaus (1997) Construction and Characterization of a 10-Genome Equivalent Yeast Artificial Chromosome Library for the Laboratory Rat,Rattus norvegicus. Genomics, 39 (3). pp. 385-392. DOI https://doi.org/10.1006/geno.1996.4494
Schalkwyk, Leonard C and Charlebois, Robert L and Doolittle, W Ford (1993) Insertion sequences on plasmid pHV1 of <i>Haloferax volcanii</i>. Canadian Journal of Microbiology, 39 (2). pp. 201-206. DOI https://doi.org/10.1139/m93-028
Charlebois, Robert L and Schalkwyk, Leonard C and Hofman, Jason D and Doolittle, W Ford (1991) Detailed physical map and set of overlapping clones covering the genome of the archaebacterium Haloferax volcanii DS2. Journal of Molecular Biology, 222 (3). pp. 509-524. DOI https://doi.org/10.1016/0022-2836(91)90493-p
Charlebois, Robert L and Hofman, Jason D and Schalkwyk, Leonard C and Lam, Wan L and Doolittle, W Ford (1989) Genome mapping in halobacteria. Canadian Journal of Microbiology, 35 (1). pp. 21-29. DOI https://doi.org/10.1139/m89-004
Cline, Steven W and Lam, Wan L and Charlebois, Robert L and Schalkwyk, Leonard C and Doolittle, W Ford (1989) Transformation methods for halophilic archaebacteria. Canadian Journal of Microbiology, 35 (1). pp. 148-152. DOI https://doi.org/10.1139/m89-022
Hofman, Jason D and Schalkwyk, Leonard C and Doolittle, W Ford (1986) ISH51: a large, degenerate family of insertion sequence-like elements in the genome of the archaehacterium,<i>Halobacterium volcanii</i>. Nucleic Acids Research, 14 (17). pp. 6983-7000. DOI https://doi.org/10.1093/nar/14.17.6983