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Jacob, Divya R and Guiblet, Wilfried M and Mamayusupova, Hulkar and Shtumpf, Mariya and Ciuta, Isabella and Ruje, Luminita and Gretton, Svetlana and Bikova, Milena and Correa, Clark and Dellow, Emily and Agrawal, Shivam P and Shafiei, Navid and Drobysevskaja, Anastasija and Armstrong, Chris M and Lam, Jonathan DG and Vainshtein, Yevhen and Clarkson, Christopher T and Thorn, Graeme J and Sohn, Kai and Pradeepa, Madapura M and Chandrasekharan, Sankaran and Brooke, Greg N and Klenova, Elena and Zhurkin, Victor B and Teif, Vladimir B (2024) Nucleosome reorganisation in breast cancer tissues. Clinical Epigenetics, 16 (1). 50-. DOI https://doi.org/10.1186/s13148-024-01656-4

Ogunjinmi, Oluwadamilola D and Abdullahi, Tukur and Somji, Riaz-Ali and Bevan, Charlotte L and Barclay, Wendy S and Temperton, Nigel and Brooke, Greg N and Giotis, Efstathios (2024) The antiviral potential of the antiandrogen enzalutamide and the viral-androgen signaling interplay in seasonal coronaviruses. Journal of Medical Virology, 96 (3). e29540-. DOI https://doi.org/10.1002/jmv.29540

Gundersen, Rebekah Anamarie and Chu, Tianyuan and Abolfathi, Kiana and Gokcen Dogan, Serap and Blair, Phoebe Elizabeth and Nago, Nyasha and Hamblin, Michael and Brooke, Greg Nicholas and Zwacka, Ralf Michael and Kafash Hoshiar, Ali and Mohr, Andrea (2023) Generation of magnetic biohybrid microrobots based on MSC.sTRAIL for targeted stem cell delivery and treatment of cancer. Cancer Nanotechnology, 14 (1). 54-. DOI https://doi.org/10.1186/s12645-023-00203-9

Pine, Angela C and Brooke, Greg N and Marco, Antonio (2023) A computational approach to identify efficient RNA cleaving 10-23 DNAzymes. NAR Genomics and Bioinformatics, 5 (1). lqac098-. DOI https://doi.org/10.1093/nargab/lqac098

Alghamdi, Rana A and Exposito-Rodriguez, Marino and Mullineaux, Philip M and Brooke, Greg N and Laissue, Philippe P (2021) Assessing Phototoxicity in a Mammalian Cell Line: How Low Levels of Blue Light Affect Motility in PC3 Cells. Frontiers in Cell and Developmental Biology, 9. 738786-. DOI https://doi.org/10.3389/fcell.2021.738786

Leach, Damien A and Brooke, Greg N and Bevan, Charlotte L (2021) Roles of steroid receptors in the lung and COVID-19. Essays in Biochemistry, 65 (6). pp. 1025-1038. DOI https://doi.org/10.1042/ebc20210005

Mohr, Andrea and Chu, Tianyuan and Clarkson, Christopher and Brooke, Greg and Teif, Vladimir and Zwacka, Ralf (2021) Fas-threshold Signalling in MSCs Promotes Pancreatic Cancer Progression and Metastasis. Cancer Letters, 519. pp. 63-77. DOI https://doi.org/10.1016/j.canlet.2021.06.017

Leach, DA and Mohr, A and Giotis, ES and Cil, E and Isac, AM and Yates, LL and Barclay, WS and Zwacka, RM and Bevan, CL and Brooke, GN (2021) The antiandrogen enzalutamide downregulates TMPRSS2 and reduces cellular entry of SARS-CoV-2 in human lung cells. Nature Communications, 12 (1). 4068-. DOI https://doi.org/10.1038/s41467-021-24342-y

Cronin, Ryan and Brooke, Greg N and Prischi, Filippo (2021) The role of the p90 ribosomal S6 kinase family in prostate cancer progression and therapy resistance. Oncogene, 40 (22). pp. 3775-3785. DOI https://doi.org/10.1038/s41388-021-01810-9

Brooke, Greg N and Prischi, Filippo (2020) Structural and functional modelling of SARS-CoV-2 entry in animal models. Scientific Reports, 10 (1). 15917-. DOI https://doi.org/10.1038/s41598-020-72528-z

Mohr, Andrea and Chu, Tianyuan and Brooke, Greg N and Zwacka, Ralf M (2019) MSC.sTRAIL Has Better Efficacy than MSC.FL-TRAIL and in Combination with AKTi Blocks Pro-Metastatic Cytokine Production in Prostate Cancer Cells. Cancers, 11 (4). p. 568. DOI https://doi.org/10.3390/cancers11040568

Pine, Angela C and Fioretti, Flavia F and Brooke, Greg N and Bevan, Charlotte L (2016) Advances in genetics: widening our understanding of prostate cancer. F1000Research, 5. p. 1512. DOI https://doi.org/10.12688/f1000research.8019.1

Brooke, Greg N and Gamble, Simon C and Hough, Michael A and Begum, Shajna and Dart, D Alwyn and Odontiadis, Michael and Powell, Sue M and Fioretti, Flavia M and Bryan, Rosie A and Waxman, Jonathan and Wait, Robin and Bevan, Charlotte L (2015) Antiandrogens Act as Selective Androgen Receptor Modulators at the Proteome Level in Prostate Cancer Cells*. Molecular & Cellular Proteomics, 14 (5). pp. 1201-1216. DOI https://doi.org/10.1074/mcp.m113.036764

Querol Cano, Laia and Lavery, Derek N and Sin, Soraya and Spanjaard, Emma and Brooke, Greg N and Tilman, Jessica D and Abroaf, Ahmed and Gaughan, Luke and Robson, Craig N and Heer, Rakesh and Mauri, Francesco and de Rooij, Johan and Driouch, Keltouma and Bevan, Charlotte L (2015) The co‐chaperone p23 promotes prostate cancer motility and metastasis. Molecular Oncology, 9 (1). pp. 295-308. DOI https://doi.org/10.1016/j.molonc.2014.08.014

Rudraraju, Bharath and Droog, Marjolein and Abdel-Fatah, Tarek MA and Zwart, Wilbert and Giannoudis, Athina and Malki, Mohammed I and Moore, David and Patel, Hetal and Shaw, Jacqui and Ellis, Ian O and Chan, Steve and Brooke, Greg N and Nevedomskaya, Ekaterina and Nigro, Christiana Lo and Carroll, Jason and Coombes, R Charles and Bevan, Charlotte and Ali, Simak and Palmieri, Carlo (2014) Phosphorylation of activating transcription factor-2 (ATF-2) within the activation domain is a key determinant of sensitivity to tamoxifen in breast cancer. Breast Cancer Research and Treatment, 147 (2). pp. 295-309. DOI https://doi.org/10.1007/s10549-014-3098-0

Fioretti, FM and Sita-Lumsden, A and Bevan, CL and Brooke, GN (2014) Revising the role of the androgen receptor in breast cancer. Journal of Molecular Endocrinology, 52 (3). R257-R265. DOI https://doi.org/10.1530/jme-14-0030

Brooke, Greg N and Powell, Sue M and Lavery, Derek N and Waxman, Jonathan and Buluwela, Laki and Ali, Simak and Bevan, Charlotte L (2014) Engineered repressors are potent inhibitors of androgen receptor activity. Oncotarget, 5 (4). pp. 959-969. DOI https://doi.org/10.18632/oncotarget.1360

Ottaviani, Silvia and Brooke, Greg N and O'Hanlon-Brown, Ciara and Waxman, Jonathan and Ali, Simak and Buluwela, Laki (2013) Characterisation of the androgen regulation of glycine N-methyltransferase in prostate cancer cells. Journal of Molecular Endocrinology, 51 (3). pp. 301-312. DOI https://doi.org/10.1530/jme-13-0169

Sita-Lumsden, Ailsa and Fletcher, Claire E and Dart, D Alwyn and Brooke, Greg N and Waxman, Jonathan and Bevan, Charlotte L (2013) Circulating Nucleic Acids as Biomarkers of Prostate Cancer. Biomarkers in Medicine, 7 (6). pp. 867-877. DOI https://doi.org/10.2217/bmm.13.104

Dart, DA and Brooke, GN and Sita-Lumsden, A and Waxman, J and Bevan, CL (2012) Reducing prohibitin increases histone acetylation, and promotes androgen independence in prostate tumours by increasing androgen receptor activation by adrenal androgens. Oncogene, 31 (43). pp. 4588-4598. DOI https://doi.org/10.1038/onc.2011.591

Reebye, Vikash and Querol Cano, Laia and Lavery, Derek N and Brooke, Greg N and Powell, Sue M and Chotai, Deepa and Walker, Marjorie M and Whitaker, Hayley C and Wait, Robin and Hurst, Helen C and Bevan, Charlotte L (2012) Role of the HSP90-Associated Cochaperone p23 in Enhancing Activity of the Androgen Receptor and Significance for Prostate Cancer. Molecular Endocrinology, 26 (10). pp. 1694-1706. DOI https://doi.org/10.1210/me.2012-1056

Grosdidier, Solène and Carbó, Laia R and Buzón, Víctor and Brooke, Greg and Nguyen, Phuong and Baxter, John D and Bevan, Charlotte and Webb, Paul and Estébanez-Perpiñá, Eva and Fernández-Recio, Juan (2012) Allosteric Conversation in the Androgen Receptor Ligand-Binding Domain Surfaces. Molecular Endocrinology, 26 (7). pp. 1078-1090. DOI https://doi.org/10.1210/me.2011-1281

Brooke, Greg N and Culley, Rachel L and Dart, D Alwyn and Mann, David J and Gaughan, Luke and McCracken, Stuart R and Robson, Craig N and Spencer-Dene, Bradley and Gamble, Simon C and Powell, Sue M and Wait, Robin and Waxman, Jonathan and Walker, Marjorie M and Bevan, Charlotte L (2011) FUS/TLS Is a Novel Mediator of Androgen-Dependent Cell-Cycle Progression and Prostate Cancer Growth. Cancer Research, 71 (3). pp. 914-924. DOI https://doi.org/10.1158/0008-5472.can-10-0874

Brooke, G and Bevan, C (2009) The Role of Androgen Receptor Mutations in Prostate Cancer Progression. Current Genomics, 10 (1). pp. 18-25. DOI https://doi.org/10.2174/138920209787581307

Brooke, GN and Parker, MG and Bevan, CL (2008) Mechanisms of androgen receptor activation in advanced prostate cancer: differential co-activator recruitment and gene expression. Oncogene, 27 (21). pp. 2941-2950. DOI https://doi.org/10.1038/sj.onc.1210955

Gamble, SC and Chotai, D and Odontiadis, M and Dart, DA and Brooke, GN and Powell, SM and Reebye, V and Varela-Carver, A and Kawano, Y and Waxman, J and Bevan, CL (2007) Prohibitin, a protein downregulated by androgens, represses androgen receptor activity. Oncogene, 26 (12). pp. 1757-1768. DOI https://doi.org/10.1038/sj.onc.1209967

Powell, SM and Brooke, GN and Whitaker, HC and Reebye, V and Gamble, SC and Chotai, D and Dart, DA and Belandia, B and Bevan, CL (2006) Mechanisms of androgen receptor repression in prostate cancer. Biochemical Society Transactions, 34 (6). pp. 1124-1127. DOI https://doi.org/10.1042/bst0341124

Vigushin, DM and Mirsaidi, N and Brooke, G and Sun, C and Pace, P and Inman, L and Moody, CJ and Coombes, RC (2004) Gliotoxin Is a Dual Inhibitor of Farnesyltransferase and Geranylgeranyltransferase I with Antitumor Activity Against Breast Cancer In Vivo. Medical Oncology, 21 (1). pp. 21-30. DOI https://doi.org/10.1385/mo:21:1:21

Vigushin, David M and Brooke, Greg and Willows, David and Coombes, R Charles and Moody, Christopher J (2003) Pyrazino[1,2- a ]indole-1,4-diones, simple analogues of gliotoxin, as selective inhibitors of geranylgeranyltransferase I. Bioorganic & Medicinal Chemistry Letters, 13 (21). pp. 3661-3663. DOI https://doi.org/10.1016/j.bmcl.2003.08.022

Marson, Charles M and Rioja, Alphonso S and Brooke, Greg and Coombes, R Charles and Vigushin, David M (2002) Cyclic acid anhydrides as a new class of potent, selective and non-peptidic inhibitors of geranylgeranyl transferase. Bioorganic & Medicinal Chemistry Letters, 12 (2). pp. 255-259. DOI https://doi.org/10.1016/s0960-894x(01)00718-1