Items where Author is "Rallis, Charalampos"

Alao, John-Patrick and Legon, Luc and Dabrowska, Aleksandra and Tricolici, Anne-Marie and Kumar, Juhi and Rallis, Charalampos (2023) Interplays of AMPK and TOR in Autophagy Regulation in Yeast. Cells, 12 (4). p. 519. DOI https://doi.org/10.3390/cells12040519

Dabrowska, Aleksandra and Kumar, Juhi and Rallis, Charalampos (2022) Nutrient-Response Pathways in Healthspan and Lifespan Regulation. Cells, 11 (9). p. 1568. DOI https://doi.org/10.3390/cells11091568

Legon, Luc and Rallis, Charalampos (2022) Genome-wide screens in yeast models towards understanding chronological lifespan regulation. Briefings in Functional Genomics, 21 (1). pp. 4-12. DOI https://doi.org/10.1093/bfgp/elab011

Martinez-Miguel, Victoria Eugenia and Lujan, Celia and Espie--Caullet, Tristan and Martinez-Martinez, Daniel and Moore, Saul and Backes, Cassandra and Gonzalez, Suam and Galimov, Evgeniy R and Brown, André EX and Halic, Mario and Tomita, Kazunori and Rallis, Charalampos and von der Haar, Tobias and Cabreiro, Filipe and Bjedov, Ivana (2021) Increased fidelity of protein synthesis extends lifespan. Cell Metabolism, 33 (11). 2288-2300.e12. DOI https://doi.org/10.1016/j.cmet.2021.08.017

Alao, John-Patrick and Legon, Luc and Rallis, Charalampos (2021) Crosstalk between the mTOR and DNA Damage Response Pathways in Fission Yeast. Cells, 10 (2). p. 305. DOI https://doi.org/10.3390/cells10020305

Rallis, Charalampos and Mülleder, Michael and Smith, Graeme and Au, Yan Zi and Ralser, Markus and Bähler, Jürg (2021) Amino acids whose intracellular levels change most during aging alter chronological lifespan of fission yeast. Journals of Gerontology - Series A, 76 (2). pp. 205-210. DOI https://doi.org/10.1093/gerona/glaa246

Alao, John P and Johansson-Sjölander, Johanna and Rallis, Charalampos and Sunnerhagen, Per (2020) Caffeine Stabilises Fission Yeast Wee1 in a Rad24-Dependent Manner but Attenuates Its Expression in Response to DNA Damage. Microorganisms, 8 (10). p. 1512. DOI https://doi.org/10.3390/microorganisms8101512

Bjedov, Ivana and Rallis, Charalampos (2020) The Target of Rapamycin Signalling Pathway in Ageing and Lifespan Regulation. Genes, 11 (9). p. 1043. DOI https://doi.org/10.3390/genes11091043

Rodríguez-López, María and Gonzalez, Suam and Hillson, Olivia and Tunnacliffe, Edward and Codlin, Sandra and Tallada, Victor A and Bähler, Jürg and Rallis, Charalampos (2020) The GATA Transcription Factor Gaf1 Represses tRNAs, Inhibits Growth, and Extends Chronological Lifespan Downstream of Fission Yeast TORC1. Cell Reports, 30 (10). 3240-3249.e4. DOI https://doi.org/10.1016/j.celrep.2020.02.058

Alao, John P and Johansson-Sjölander, Johanna and Rallis, Charalampos and Sunnerhagen, Per (2020) Caffeine stabilises fission yeast Wee1 in a Rad24-dependent manner but attenuates its expression in response to DNA damage identifying a putative role for TORC1 in mediating its effects on cell cycle progression. DOI https://doi.org/10.1101/2020.01.22.915231

Rodriguez-Lopez, Maria and Gonzalez, Suam and Hillson, Olivia and Tunnacliffe, Edward and Codlin, Sandra and Tallada, Victor and Bahler, Jurg and Rallis, Charalampos (2019) The GATA transcription factor Gaf1 represses tRNA genes, inhibits growth, and extends chronological lifespan downstream of fission yeast TORC1. bioarxiv. DOI https://doi.org/10.1101/700286 (Unpublished)

Pai, Chen-Chun and Hsu, Kuo-Feng and Durley, Samuel C and Keszthelyi, Andrea and Kearsey, Stephen E and Rallis, Charalampos and Folkes, Lisa K and Deegan, Rachel and Wilkins, Sarah E and Pfister, Sophia X and De León, Nagore and Schofield, Christopher J and Bähler, Jürg and Carr, Antony M and Humphrey, Timothy C (2019) An essential role for dNTP homeostasis following CDK-induced replication stress. Journal of Cell Science, 132 (6). jcs226969-. DOI https://doi.org/10.1242/jcs.226969

Hillson, Olivia and Gonzalez, Suam and Rallis, Charalampos (2018) Prospects of Pharmacological Interventions to Organismal Aging. BioMolecular Concepts, 9 (1). pp. 200-215. DOI https://doi.org/10.1515/bmc-2018-0018

Ellis, David A and Mustonen, Ville and Rodríguez-López, María and Rallis, Charalampos and Malecki, Michał and Jeffares, Daniel C and Bähler, Jürg (2018) Uncovering Natural Longevity Alleles from Intercrossed Pools of Aging Fission Yeast Cells. Genetics, 210 (2). pp. 733-744. DOI https://doi.org/10.1534/genetics.118.301262

Atkinson, Sophie R and Marguerat, Samuel and Bitton, Danny A and Rodríguez-López, Maria and Rallis, Charalampos and Lemay, Jean-François and Cotobal, Cristina and Malecki, Michal and Smialowski, Pawel and Mata, Juan and Korber, Philipp and Bachand, François and Bähler, Jürg (2018) Long noncoding RNA repertoire and targeting by nuclear exosome, cytoplasmic exonuclease, and RNAi in fission yeast. RNA, 24 (9). pp. 1195-1213. DOI https://doi.org/10.1261/rna.065524.118

Hoyos-Manchado, Rafael and Reyes-Martín, Félix and Rallis, Charalampos and Gamero-Estévez, Enrique and Rodríguez-Gómez, Pablo and Quintero-Blanco, Juan and Bähler, Jürg and Jiménez, Juan and Tallada, Víctor A (2017) RNA metabolism is the primary target of formamide in vivo. Scientific Reports, 7 (1). 15895-. DOI https://doi.org/10.1038/s41598-017-16291-8

Gonzalez, Suam and Rallis, Charalampos (2017) The TOR Signaling Pathway in Spatial and Temporal Control of Cell Size and Growth. Frontiers in Cell and Developmental Biology, 5 (JUN). 61-. DOI https://doi.org/10.3389/fcell.2017.00061

Rallis, Charalampos and Townsend, StJohn and Bähler, Jürg (2017) Genetic interactions and functional analyses of the fission yeast gsk3 and amk2 single and double mutants defective in TORC1-dependent processes. Scientific Reports, 7 (1). 44257-. DOI https://doi.org/10.1038/srep44257

Jeffares, Daniel C and Jolly, Clemency and Hoti, Mimoza and Speed, Doug and Shaw, Liam and Rallis, Charalampos and Balloux, Francois and Dessimoz, Christophe and Bähler, Jürg and Sedlazeck, Fritz J (2017) Transient structural variations have strong effects on quantitative traits and reproductive isolation in fission yeast. Nature Communications, 8 (1). 14061-. DOI https://doi.org/10.1038/ncomms14061

Malecki, Michal and Bitton, Danny A and Rodríguez-López, Maria and Rallis, Charalampos and Calavia, Noelia Garcia and Smith, Graeme C and Bähler, Jürg (2016) Functional and regulatory profiling of energy metabolism in fission yeast. Genome Biology, 17 (1). 240-. DOI https://doi.org/10.1186/s13059-016-1101-2

Brault, Ariane and Rallis, Charalampos and Normant, Vincent and Garant, Jean-Michel and Bähler, Jürg and Labbé, Simon (2016) Php4 Is a Key Player for Iron Economy in Meiotic and Sporulating Cells. G3: Genes, Genomes, Genetics, 6 (10). pp. 3077-3095. DOI https://doi.org/10.1534/g3.116.031898

Bischof, Leanne and Převorovský, Martin and Rallis, Charalampos and Jeffares, Daniel C and Arzhaeva, Yulia and Bähler, Jürg (2016) Spotsizer: High-throughput quantitative analysis of microbial growth. BioTechniques, 61 (4). pp. 191-201. DOI https://doi.org/10.2144/000114459

Vishwanatha, Akshay and Rallis, Charalampos and Bevkal Subramanyaswamy, Shubha and D'Souza, Cletus Joseph Michael and Bähler, Jürg and Schweingruber, Martin Ernst (2016) Identification of nuclear genes affecting 2-Deoxyglucose resistance in Schizosaccharomyces pombe. FEMS Yeast Research, 16 (6). fow061-fow061. DOI https://doi.org/10.1093/femsyr/fow061

Tomalin, Lewis Elwood and Day, Alison Michelle and Underwood, Zoe Elizabeth and Smith, Graham Robert and Dalle Pezze, Piero and Rallis, Charalampos and Patel, Waseema and Dickinson, Bryan Craig and Bähler, Jürg and Brewer, Thomas Francis and Chang, Christopher Joh-Leung and Shanley, Daryl Pierson and Veal, Elizabeth Ann (2016) Increasing extracellular H₂O₂ produces a bi-phasic response in intracellular H₂O₂, with peroxiredoxin hyperoxidation only triggered once the cellular H₂O₂-buffering capacity is overwhelmed. Free Radical Biology and Medicine, 95. pp. 333-348. DOI https://doi.org/10.1016/j.freeradbiomed.2016.02.035

Rallis, Charalampos and Bähler, Jürg (2016) Cell-based screens and phenomics with fission yeast. Critical Reviews in Biochemistry and Molecular Biology, 51 (2). pp. 86-95. DOI https://doi.org/10.3109/10409238.2015.1103205

Bond, Michael and Brown, Rachel and Rallis, Charalampos and Bahler, Jurg and Mole, Sara (2015) A central role for TOR signalling in a yeast model for juvenile CLN3 disease. Microbial Cell, 2 (12). pp. 466-480. DOI https://doi.org/10.15698/mic2015.12.241

Bitton, Danny A and Atkinson, Sophie R and Rallis, Charalampos and Smith, Graeme C and Ellis, David A and Chen, Yuan YC and Malecki, Michal and Codlin, Sandra and Lemay, Jean-François and Cotobal, Cristina and Bachand, François and Marguerat, Samuel and Mata, Juan and Bähler, Jürg (2015) Widespread exon skipping triggers degradation by nuclear RNA surveillance in fission yeast. Genome Research, 25 (6). pp. 884-896. DOI https://doi.org/10.1101/gr.185371.114

Jeffares, Daniel C and Rallis, Charalampos and Rieux, Adrien and Speed, Doug and Převorovský, Martin and Mourier, Tobias and Marsellach, Francesc X and Iqbal, Zamin and Lau, Winston and Cheng, Tammy MK and Pracana, Rodrigo and Mülleder, Michael and Lawson, Jonathan LD and Chessel, Anatole and Bala, Sendu and Hellenthal, Garrett and O'Fallon, Brendan and Keane, Thomas and Simpson, Jared T and Bischof, Leanne and Tomiczek, Bartlomiej and Bitton, Danny A and Sideri, Theodora and Codlin, Sandra and Hellberg, Josephine EEU and van Trigt, Laurent and Jeffery, Linda and Li, Juan-Juan and Atkinson, Sophie and Thodberg, Malte and Febrer, Melanie and McLay, Kirsten and Drou, Nizar and Brown, William and Hayles, Jacqueline and Carazo Salas, Rafael E and Ralser, Markus and Maniatis, Nikolas and Balding, David J and Balloux, Francois and Durbin, Richard and Bähler, Jürg (2015) The genomic and phenotypic diversity of Schizosaccharomyces pombe. Nature Genetics, 47 (3). pp. 235-241. DOI https://doi.org/10.1038/ng.3215

Sideri, Theodora and Rallis, Charalampos and Bitton, Danny A and Lages, Bruno M and Suo, Fang and Rodríguez-López, María and Du, Li-Lin and Bähler, Jürg (2015) Parallel profiling of fission yeast deletion mutants for proliferation and for lifespan during long-term quiescence. G3: Genes, Genomes, Genetics, 5 (1). pp. 145-155. DOI https://doi.org/10.1534/g3.114.014415

Sofola-Adesakin, Oyinkan and Castillo-Quan, Jorge I and Rallis, Charalampos and Tain, Luke S and Bjedov, Ivana and Rogers, Iain and Li, Li and Martinez, Pedro and Khericha, Mobina and Cabecinha, Melissa and Bähler, Jürg and Partridge, Linda (2014) Lithium suppresses Aβ pathology by inhibiting translation in an adult Drosophila model of Alzheimer's disease. Frontiers in Aging Neuroscience, 6 (JUL). 190-. DOI https://doi.org/10.3389/fnagi.2014.00190

Bitton, Danny A and Rallis, Charalampos and Jeffares, Daniel C and Smith, Graeme C and Chen, Yuan YC and Codlin, Sandra and Marguerat, Samuel and Bähler, Jürg (2014) LaSSO, a strategy for genome-wide mapping of intronic lariats and branch points using RNA-seq. Genome Research, 24 (7). pp. 1169-1179. DOI https://doi.org/10.1101/gr.166819.113

Rallis, Charalampos and López-Maury, Luis and Georgescu, Teodora and Pancaldi, Vera and Bähler, Jürg (2014) Systematic screen for mutants resistant to TORC1 inhibition in fission yeast reveals genes involved in cellular ageing and growth. Biology Open, 3 (2). pp. 161-171. DOI https://doi.org/10.1242/bio.20147245

Rallis, Charalampos and Codlin, Sandra and Bähler, Jürg (2013) TORC1 signaling inhibition by rapamycin and caffeine affect lifespan, global gene expression, and cell proliferation of fission yeast. Aging Cell, 12 (4). pp. 563-573. DOI https://doi.org/10.1111/acel.12080

Rallis, Charalampos and Bähler, Jürg (2013) Inhibition of TORC1 signaling and increased lifespan: gained in translation? Aging, 5 (5). pp. 335-336. DOI https://doi.org/10.18632/aging.100560

Pancaldi, Vera and Saraç, Omer S and Rallis, Charalampos and McLean, Janel R and Převorovský, Martin and Gould, Kathleen and Beyer, Andreas and Bähler, Jürg (2012) Predicting the fission yeast protein interaction network. G3: Genes, Genomes, Genetics, 2 (4). pp. 453-467. DOI https://doi.org/10.1534/g3.111.001560

Převorovský, Martin and Rallis, Charalampos (2011) Bright days for yeast research. Genome Biology, 12 (5). p. 305. DOI https://doi.org/10.1186/gb-2011-12-5-305

Rallis, Charalampos and Pinchin, Sheena M and Ish-Horowicz, David (2010) Cell-autonomous integrin control of Wnt and Notch signalling during somitogenesis. Development, 137 (21). pp. 3591-3601. DOI https://doi.org/10.1242/dev.050070

Maydan, Mykola and McDonald, Paul C and Sanghera, Jasbinder and Yan, Jun and Rallis, Charalampos and Pinchin, Sheena and Hannigan, Gregory E and Foster, Leonard J and Ish-Horowicz, David and Walsh, Michael P and Dedhar, Shoukat (2010) Integrin-linked kinase is a functional Mn²⁺-dependent protein kinase that regulates glycogen synthase kinase-3β (GSK-3beta) phosphorylation. PLoS One, 5 (8). e12356-e12356. DOI https://doi.org/10.1371/journal.pone.0012356

Rallis, Charalampos (2009) New tricks for an old-favorite model. Genome Biology, 10 (9). p. 315. DOI https://doi.org/10.1186/gb-2009-10-9-315

Hanisch, Anja and Vezzaro, Annalisa and Rallis, Charalampos (2008) Elucidating developmental gene networks. Genome Biology, 9 (6). p. 310. DOI https://doi.org/10.1186/gb-2008-9-6-310

Bazigou, Eleni and Rallis, Charalampos (2007) Cell signaling and cancer. Genome Biology, 8 (7). p. 310. DOI https://doi.org/10.1186/gb-2007-8-7-310

Rallis, Charalampos (2007) Chickens get their place in the sun. Genome Biology, 8 (5). p. 306. DOI https://doi.org/10.1186/gb-2007-8-5-306

Rallis, Charalampos (2006) Developmental genomics reaches new heights. Genome Biology, 7 (10). p. 329. DOI https://doi.org/10.1186/gb-2006-7-10-329

Rallis, Charalampos and Del Buono, Jo and Logan, Malcolm PO (2005) Tbx3 can alter limb position along the rostrocaudal axis of the developing embryo. Development, 132 (8). pp. 1961-1970. DOI https://doi.org/10.1242/dev.01787

Rallis, Charalampos and Bruneau, Benoit G and Del Buono, Jo and Seidman, Christine E and Seidman, JG and Nissim, Sahar and Tabin, Clifford J and Logan, Malcolm PO (2003) Tbx5 is required for forelimb bud formation and continued outgrowth. Development, 130 (12). pp. 2741-2751. DOI https://doi.org/10.1242/dev.00473

Rallis, Charalampos and Stamataki, Despina and Pontikakis, Spyros and Mankoo, Baljnder S and Karagogeos, Domna (2001) Isolation of the avian homologue of the homeobox gene Mox2 and analysis of its expression pattern in developing somites and limbs. Mechanisms of Development, 104 (1-2). pp. 121-124. DOI https://doi.org/10.1016/s0925-4773(01)00354-9