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Vellame, Dorothea Seiler and Shireby, Gemma and MacCalman, Ailsa and Dempster, Emma L and Burrage, Joe and Gorrie-Stone, Tyler and Schalkwyk, Leonard S and Mill, Jonathan and Hannon, Eilis (2023) Uncertainty quantification of reference-based cellular deconvolution algorithms. Epigenetics, 18 (1). pp. 1217-1254. DOI https://doi.org/10.1080/15592294.2022.2137659

Wang, Yucheng and Grant, Olivia and Zhai, Xiaojun and McDonald-Maier, Klaus and Schalkwyk, Leonard (2023) Insights into ageing rates comparison across tissues from recalibrating cerebellum DNA methylation clock. GeroScience, 46 (1). pp. 39-56. DOI https://doi.org/10.1007/s11357-023-00871-w

Devall, Matthew and Soanes, Darren M and Smith, Adam R and Dempster, Emma L and Smith, Rebecca G and Burrage, Joe and Iatrou, Artemis and Hannon, Eilis and Troakes, Claire and Moore, Karen and O'Neill, Paul and Al-Sarraj, Safa and Schalkwyk, Leonard and Mill, Jonathan and Weedon, Michael and Lunnon, Katie (2023) Genome-wide characterization of mitochondrial DNA methylation in human brain. Frontiers in Endocrinology, 13. 1059120-. DOI https://doi.org/10.3389/fendo.2022.1059120

Bao, Yanchun and Gorrie-Stone, Tyler and Hannon, Eilis and Hughes, Amanda and Andrayas, Alexandria and Neilson, Grant and Burrage, Joe and Mill, Jonathon and Schalkwyk, Leonard and Kumari, Meena (2022) Social mobility across the lifecourse and DNA methylation age acceleration in adults in the UK. Scientific Reports, 12 (1). p. 22284. DOI https://doi.org/10.1038/s41598-022-26433-2

Flynn, Robert and Washer, Sam and Jeffries, Aaron R and Andrayas, Alexandria and Shireby, Gemma and Kumari, Meena and Schalkwyk, Leonard C and Mill, Jonathan and Hannon, Eilis (2022) Evaluation of nanopore sequencing for epigenetic epidemiology: a comparison with DNA methylation microarrays. Human Molecular Genetics, 31 (18). pp. 3181-3190. DOI https://doi.org/10.1093/hmg/ddac112

Wang, Yucheng and Gorrie-Stone, Tyler J and Grant, Olivia A and Andrayas, Alexandria D and Zhai, Xiaojun and McDonald-Maier, Klaus D and Schalkwyk, Leonard C (2022) InterpolatedXY: a two-step strategy to normalise DNA methylation microarray data avoiding sex bias. Bioinformatics, 38 (16). pp. 3950-3957. DOI https://doi.org/10.1093/bioinformatics/btac436

Grant, Olivia A and Wang, Yucheng and Kumari, Meena and Zabet, Nicolae Radu and Schalkwyk, Leonard (2022) Characterising sex differences of autosomal DNA methylation in whole blood using the Illumina EPIC array. Clinical Epigenetics, 14 (1). 62-. DOI https://doi.org/10.1186/s13148-022-01279-7

Leung, Szi Kay and Jeffries, Aaron R and Castanho, Isabel and Jordan, Ben T and Moore, Karen and Davies, Jonathan P and Dempster, Emma L and Bray, Nicholas J and O'Neill, Paul and Tseng, Elizabeth and Ahmed, Zeshan and Collier, David A and Jeffery, Erin D and Prabhakar, Shyam and Schalkwyk, Leonard and Jops, Connor and Gandal, Michael J and Sheynkman, Gloria M and Hannon, Eilis and Mill, Jonathan (2021) Full-length transcript sequencing of human and mouse cerebral cortex identifies widespread isoform diversity and alternative splicing. Cell Reports, 37 (7). p. 110022. DOI https://doi.org/10.1016/j.celrep.2021.110022

Min, Josine L and Hemani, Gibran and Kumari, Meena and Schalkwyk, Leonard C and et al (2021) Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation. Nature Genetics, 53 (9). pp. 1311-1321. DOI https://doi.org/10.1038/s41588-021-00923-x

Wang, Yucheng and Hannon, Eilis and Grant, Olivia and Gorrie-Stone, Tyler and Kumari, Meena and Mill, Jonathan and Zhai, Xiaojun and McDonald-Maier, Klaus and Schalkwyk, Leonard (2021) DNA methylation-based sex classifier to predictsex and identify sex chromosome aneuploidy. BMC Genomics, 22 (1). 484-. DOI https://doi.org/10.1186/s12864-021-07675-2

Smith, Rebecca G and Pishva, Ehsan and Shireby, Gemma and Smith, Adam R and Roubroeks, Janou AY and Hannon, Eilis and Wheildon, Gregory and Mastroeni, Diego and Gasparoni, Gilles and Riemenschneider, Matthias and Giese, Armin and Sharp, Andrew J and Schalkwyk, Leonard and Haroutunian, Vahram and Viechtbauer, Wolfgang and van den Hove, Daniel LA and Weedon, Michael and Brokaw, Danielle and Francis, Paul T and Thomas, Alan J and Love, Seth and Morgan, Kevin and Walter, Jörn and Coleman, Paul D and Bennett, David A and De Jager, Philip L and Mill, Jonathan and Lunnon, Katie (2021) A meta-analysis of epigenome-wide association studies in Alzheimer's disease highlights novel differentially methylated loci across cortex. Nature Communications, 12 (1). 3517-. DOI https://doi.org/10.1038/s41467-021-23243-4

Hannon, Eilis and Dempster, Emma L and Mansell, Georgina and Burrage, Joe and Bass, Nick and Bohlken, Marc M and Corvin, Aiden and Curtis, Charles J and Dempster, David and Di Forti, Marta and Dinan, Timothy G and Donohoe, Gary and Gaughran, Fiona and Gill, Michael and Gillespie, Amy and Gunasinghe, Cerisse and Hulshoff, Hilleke E and Hultman, Christina M and Johansson, Viktoria and Kahn, René S and Kaprio, Jaakko and Kenis, Gunter and Kowalec, Kaarina and MacCabe, James and McDonald, Colm and McQuillin, Andrew and Morris, Derek W and Murphy, Kieran C and Mustard, Colette J and Nenadic, Igor and O'Donovan, Michael C and Quattrone, Diego and Richards, Alexander L and Rutten, Bart Pf and St Clair, David and Therman, Sebastian and Toulopoulou, Timothea and Van Os, Jim and Waddington, John L and Wellcome Trust Case Control Consortium (WTCCC) and CRESTAR consortium and Sullivan, Patrick and Vassos, Evangelos and Breen, Gerome and Collier, David Andrew and Murray, Robin M and Schalkwyk, Leonard S and Mill, Jonathan (2021) DNA methylation meta-analysis reveals cellular alterations in psychosis and markers of treatment-resistant schizophrenia. eLife, 10. pp. 1-53. DOI https://doi.org/10.7554/elife.58430

Shireby, Gemma L and Davies, Jonathan P and Francis, Paul T and Burrage, Joe and Walker, Emma M and Neilson, Grant WA and Dahir, Aisha and Thomas, Alan J and Love, Seth and Smith, Rebecca G and Lunnon, Katie and Kumari, Meena and Schalkwyk, Leonard C and Morgan, Kevin and Brookes, Keeley and Hannon, Eilis and Mill, Jonathan (2020) Recalibrating the epigenetic clock: implications for assessing biological age in the human cortex. Brain: a journal of neurology, 143 (12). pp. 3763-3775. DOI https://doi.org/10.1093/brain/awaa334

Åsenius, Fredrika and Gorrie-Stone, Tyler J and Brew, Ama and Panchbhaya, Yasmin and Williamson, Elizabeth and Schalkwyk, Leonard C and Rakyan, Vardhman K and Holland, Michelle L and Marzi, Sarah J and Williams, David J (2020) The DNA methylome of human sperm is distinct from blood with little evidence for tissue-consistent obesity associations. PLoS Genetics, 16 (10). e1009035-e1009035. DOI https://doi.org/10.1371/journal.pgen.1009035

El Khoury, Louis Y and Gorrie-Stone, Tyler J and Smart, Melissa and Hughes, Amanda and Bao, Yanchun and Andrayas, Alexandria and Burrage, Joe and Hannon, Eilis and Kumari, Meena and Mill, Jonathan and Schalkwyk, Leonard (2019) Systematic under-estimation of the epigenetic clock and age acceleration in older subjects. Genome Biology, 20 (1). 283-. DOI https://doi.org/10.1186/s13059-019-1810-4

Bell, Christopher G and Lowe, Robert and Adams, Peter D and Baccarelli, Andrea A and Beck, Stephan and Bell, Jordana T and Christensen, Brock C and Gladyshev, Vadim N and Heijmans, Bastiaan T and Horvath, Steve and Ideker, Trey and Issa, Jean-Pierre J and Kelsey, Karl T and Marioni, Riccardo E and Reik, Wolf and Relton, Caroline L and Schalkwyk, Leonard C and Teschendorff, Andrew E and Wagner, Wolfgang and Zhang, Kang and Rakyan, Vardhman K (2019) DNA methylation aging clocks: challenges and recommendations. Genome Biology, 20 (1). 249-. DOI https://doi.org/10.1186/s13059-019-1824-y

Saffari, Ayden and Arno, Matt and Nasser, Eric and Ronald, Angelica and Wong, Chloe CY and Schalkwyk, Leonard C and Mill, Jonathan and Dudbridge, Frank and Meaburn, Emma L (2019) RNA sequencing of identical twins discordant for autism reveals blood-based signatures implicating immune and transcriptional dysregulation. Molecular Autism, 10 (1). p. 38. DOI https://doi.org/10.1186/s13229-019-0285-1

Wong, CCY and Smith, RG and Hannon, E and Ramaswami, G and Parikshak, NN and Assary, E and Troakes, C and Poschmann, J and Schalkwyk, LC and Sun, W and Prabhakar, S and Geschwind, DH and Mill, J (2019) Genome-wide DNA methylation profiling identifies convergent molecular signatures associated with idiopathic and syndromic autism in post-mortem human brain tissue. Human Molecular Genetics, 28 (13). pp. 2201-2211. DOI https://doi.org/10.1093/hmg/ddz052

Mansell, Georgina and Gorrie-Stone, Tyler J and Bao, Yanchun and Kumari, Meena and Schalkwyk, Leonard S and Mill, Jonathan and Hannon, Eilis (2019) Guidance for DNA methylation studies: statistical insights from the Illumina EPIC array. BMC Genomics, 20 (1). 366-. DOI https://doi.org/10.1186/s12864-019-5761-7

Gorrie-Stone, TJ and Smart, MC and Saffari, A and Malki, K and Hannon, E and Burrage, J and Mill, J and Kumari, M and Schalkwyk, LC (2019) Bigmelon: tools for analysing large DNA methylation datasets. Bioinformatics, 35 (6). pp. 981-986. DOI https://doi.org/10.1093/bioinformatics/bty713

Hannon, Eilis and Marzi, Sarah J and Schalkwyk, Leonard S and Mill, Jonathan (2019) Genetic risk variants for brain disorders are enriched in cortical H3K27ac domains. Molecular Brain, 12 (1). 7-. DOI https://doi.org/10.1186/s13041-019-0429-4

Smith, RG and Hannon, E and De Jager, PL and Chibnik, L and Lott, SJ and Condliffe, D and Smith, AR and Haroutunian, V and Troakes, C and Al-Sarraj, S and Bennett, DA and Powell, J and Lovestone, S and Schalkwyk, L and Mill, J and Lunnon, K (2018) Elevated DNA methylation across a 48-kb region spanning the HOXA gene cluster is associated with Alzheimer's disease neuropathology. Alzheimer's and Dementia, 14 (12). pp. 1580-1588. DOI https://doi.org/10.1016/j.jalz.2018.01.017

O’Brien, Heath E and Hannon, Eilis and Hill, Matthew J and Toste, Carolina C and Robertson, Matthew J and Morgan, Joanne E and McLaughlin, Gemma and Lewis, Cathryn M and Schalkwyk, Leonard C and Hall, Lynsey S and Pardiñas, Antonio F and Owen, Michael J and O’Donovan, Michael C and Mill, Jonathan and Bray, Nicholas J (2018) Expression quantitative trait loci in the developing human brain and their enrichment in neuropsychiatric disorders. Genome Biology, 19 (1). 194-. DOI https://doi.org/10.1186/s13059-018-1567-1

Hannon, Ellis and Gorrie-Stone, Tyler J and Smart, Melissa C and Burrage, Joe and Hughes, Amanda and Bao, Yanchun and Kumari, Meena and Schalkwyk, Leonard C and Mill, Jonathan (2018) Leveraging DNA-Methylation Quantitative-Trait Loci to Characterize the Relationship between Methylomic Variation, Gene Expression, and Complex Traits. The American Journal of Human Genetics, 103 (5). pp. 654-665. DOI https://doi.org/10.1016/j.ajhg.2018.09.007

Hughes, Amanda and Smart, Melissa and Gorrie-Stone, Tyler and Hannon, Eilis and Mill, Jonathan and Bao, Yanchun and Burrage, Joe and Schalkwyk, Leo and Kumari, Meena (2018) Socioeconomic Position and DNA Methylation Age Acceleration across the Lifecourse. American Journal of Epidemiology, 187 (11). pp. 2346-2354. DOI https://doi.org/10.1093/aje/kwy155

Marzi, Sarah J and Leung, Szi Kay and Ribarska, Teodora and Hannon, Eilis and Smith, Adam R and Pishva, Ehsan and Poschmann, Jeremie and Moore, Karen and Troakes, Claire and Al-Sarraj, Safa and Beck, Stephan and Newman, Stuart and Lunnon, Katie and Schalkwyk, Leonard C and Mill, Jonathan (2018) A histone acetylome-wide association study of Alzheimer’s disease identifies disease-associated H3K27ac differences in the entorhinal cortex. Nature Neuroscience, 21 (11). pp. 1618-1627. DOI https://doi.org/10.1038/s41593-018-0253-7

Rutten, BPF and Vermetten, E and Vinkers, CH and Ursini, G and Daskalakis, NP and Pishva, E and de Nijs, L and Houtepen, LC and Eijssen, L and Jaffe, AE and Kenis, G and Viechtbauer, W and van den Hove, D and Schraut, KG and Lesch, K-P and Kleinman, JE and Hyde, TM and Weinberger, DR and Schalkwyk, L and Lunnon, K and Mill, J and Cohen, H and Yehuda, R and Baker, DG and Maihofer, AX and Nievergelt, CM and Geuze, E and Boks, MPM (2018) Longitudinal analyses of the DNA methylome in deployed military servicemen identify susceptibility loci for post-traumatic stress disorder. Molecular Psychiatry, 23 (5). pp. 1145-1156. DOI https://doi.org/10.1038/mp.2017.120

Devall, Matthew and Smith, Rebecca G and Jeffries, Aaron and Hannon, Eilis and Davies, Matthew N and Schalkwyk, Leonard and Mill, Jonathan and Weedon, Michael and Lunnon, Katie (2017) Regional differences in mitochondrial DNA methylation in human post-mortem brain tissue. Clinical Epigenetics, 9 (1). 47-. DOI https://doi.org/10.1186/s13148-017-0337-3

Spiers, H and Hannon, E and Schalkwyk, LC and Bray, NJ and Mill, J (2017) 5-hydroxymethylcytosine is highly dynamic across human fetal brain development. BMC Genomics, 18 (1). 738-. DOI https://doi.org/10.1186/s12864-017-4091-x

Lunnon, Katie and Keohane, Aoife and Pidsley, Ruth and Newhouse, Stephen and Riddoch-Contreras, Joanna and Thubron, Elisabeth B and Devall, Matthew and Soininen, Hikka and Kłoszewska, Iwona and Mecocci, Patrizia and Tsolaki, Magda and Vellas, Bruno and Schalkwyk, Leonard and Dobson, Richard and Malik, Afshan N and Powell, John and Lovestone, Simon and Hodges, Angela (2017) Mitochondrial genes are altered in blood early in Alzheimer's disease. Neurobiology of Aging, 53. pp. 36-47. DOI https://doi.org/10.1016/j.neurobiolaging.2016.12.029

Janecka, Magdalena and Haworth, Claire MA and Ronald, Angelica and Krapohl, Eva and Happé, Francesca and Mill, Jonathan and Schalkwyk, Leonard C and Fernandes, Cathy and Reichenberg, Abraham and Rijsdijk, Frühling (2017) Paternal Age Alters Social Development in Offspring. Journal of the American Academy of Child & Adolescent Psychiatry, 56 (5). pp. 383-390. DOI https://doi.org/10.1016/j.jaac.2017.02.006

Malki, Karim and Tosto, Maria Grazia and Mouriño‐Talín, Héctor and Rodríguez‐Lorenzo, Sabela and Pain, Oliver and Jumhaboy, Irfan and Liu, Tina and Parpas, Panos and Newman, Stuart and Malykh, Artem and Carboni, Lucia and Uher, Rudolf and McGuffin, Peter and Schalkwyk, Leonard C and Bryson, Kevin and Herbster, Mark (2017) Highly polygenic architecture of antidepressant treatment response: Comparative analysis of SSRI and NRI treatment in an animal model of depression. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 174 (3). pp. 235-250. DOI https://doi.org/10.1002/ajmg.b.32494

Janecka, M and Marzi, SJ and Parsons, MJ and Liu, L and Paya-Cano, JL and Smith, RG and Fernandes, C and Schalkwyk, LC (2017) Genetic polymorphisms and their association with brain and behavioural measures in heterogeneous stock mice. Scientific Reports, 7 (1). 41204-. DOI https://doi.org/10.1038/srep41204

Janecka, M and Mill, J and Basson, MA and Goriely, A and Spiers, H and Reichenberg, A and Schalkwyk, LC and Fernandes, C (2017) Advanced paternal age effects in neurodevelopmental disorders?review of potential underlying mechanisms. Translational Psychiatry, 7 (1). e1019-e1019. DOI https://doi.org/10.1038/tp.2016.294

Viana, J and Hannon, E and Dempster, E and Pidsley, R and Macdonald, R and Knox, O and Spiers, H and Troakes, C and Al-Saraj, S and Turecki, G and Schalkwyk, LC and Mill, J (2017) Schizophrenia-associated methylomic variation: molecular signatures of disease and polygenic risk burden across multiple brain regions. Human Molecular Genetics, 26 (1). pp. 210-225. DOI https://doi.org/10.1093/hmg/ddw373

Lunnon, Katie and Hannon, Eilis and Smith, Rebecca G and Dempster, Emma and Wong, Chloe and Burrage, Joe and Troakes, Claire and Al-Sarraj, Safa and Kepa, Agnieszka and Schalkwyk, Leonard and Mill, Jonathan (2016) Variation in 5-hydroxymethylcytosine across human cortex and cerebellum. Genome Biology, 17 (1). 27-. DOI https://doi.org/10.1186/s13059-016-0871-x

Hannon, Eilis and Dempster, Emma and Viana, Joana and Burrage, Joe and Smith, Adam R and Macdonald, Ruby and St Clair, David and Mustard, Colette and Breen, Gerome and Therman, Sebastian and Kaprio, Jaakko and Toulopoulou, Timothea and Pol, Hilleke E Hulshoff and Bohlken, Marc M and Kahn, Rene S and Nenadic, Igor and Hultman, Christina M and Murray, Robin M and Collier, David A and Bass, Nick and Gurling, Hugh and McQuillin, Andrew and Schalkwyk, Leonard and Mill, Jonathan (2016) An integrated genetic-epigenetic analysis of schizophrenia: evidence for co-localization of genetic associations and differential DNA methylation. Genome Biology, 17 (1). 176-. DOI https://doi.org/10.1186/s13059-016-1041-x

Smith, Adam R and Smith, Rebecca G and Condliffe, Daniel and Hannon, Eilis and Schalkwyk, Leonard and Mill, Jonathan and Lunnon, Katie (2016) Increased DNA methylation near TREM2 is consistently seen in the superior temporal gyrus in Alzheimer's disease brain. Neurobiology of Aging, 47. pp. 35-40. DOI https://doi.org/10.1016/j.neurobiolaging.2016.07.008

Malki, Karim and Du Rietz, Ebba and Crusio, Wim E and Pain, Oliver and Paya‐Cano, Jose and Karadaghi, Rezhaw L and Sluyter, Frans and de Boer, Sietse F and Sandnabba, Kenneth and Schalkwyk, Leonard C and Asherson, Philip and Tosto, Maria Grazia (2016) Transcriptome analysis of genes and gene networks involved in aggressive behavior in mouse and zebrafish. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 171 (6). pp. 827-838. DOI https://doi.org/10.1002/ajmg.b.32451

Malki, K and Tosto, MG and Pain, O and Sluyter, F and Mineur, YS and Crusio, WE and de Boer, S and Sandnabba, KN and Kesserwani, J and Robinson, E and Schalkwyk, LC and Asherson, P (2016) Comparative mRNA analysis of behavioral and genetic mouse models of aggression. American Journal of Medical Genetics Part B-Neuropsychiatric Genetics, 171 (3). pp. 427-436. DOI https://doi.org/10.1002/ajmg.b.32424

Carter, Kim W and Carter, KW and Francis, RW and Bresnahan, M and Gissler, M and Grønborg, TK and Gross, R and Gunnes, N and Hammond, G and Hornig, M and Hultman, CM and Huttunen, J and Langridge, A and Leonard, H and Newman, S and Parner, ET and Petersson, G and Reichenberg, A and Sandin, S and Schendel, DE and Schalkwyk, L and Sourander, A and Steadman, C and Stoltenberg, C and Suominen, A and Surén, P and Susser, E and Sylvester Vethanayagam, A and Yusof, Z (2016) ViPAR: a software platform for the Virtual Pooling and Analysis of Research Data. International Journal of Epidemiology, 45 (2). pp. 408-416. DOI https://doi.org/10.1093/ije/dyv193

Houtepen, LC and Vinkers, CH and Carrillo-Roa, T and Hiemstra, M and van Lier, PA and Meeus, W and Branje, S and Heim, CM and Nemeroff, CB and Mill, J and Schalkwyk, LC and Creyghton, MP and Kahn, RS and Jo�ls, M and Binder, EB and Boks, MPM (2016) Genome-wide DNA methylation levels and altered cortisol stress reactivity following childhood trauma in humans. Nature Communications, 7 (1). creators-Schalkwyk=3ALeonard_C=3A=3A. DOI https://doi.org/10.1038/ncomms10967

Marzi, Sarah J and Meaburn, Emma L and Dempster, Emma L and Lunnon, Katie and Paya-Cano, Jose L and Smith, Rebecca G and Volta, Manuela and Troakes, Claire and Schalkwyk, Leonard C and Mill, Jonathan (2016) Tissue-specific patterns of allelically-skewed DNA methylation. Epigenetics, 11 (1). pp. 24-35. DOI https://doi.org/10.1080/15592294.2015.1127479

Hannon, Eilis and Spiers, Helen and Viana, Joana and Pidsley, Ruth and Burrage, Joe and Murphy, Therese M and Troakes, Claire and Turecki, Gustavo and O'Donovan, Michael C and Schalkwyk, Leonard C and Bray, Nicholas J and Mill, Jonathan (2016) Methylation QTLs in the developing brain and their enrichment in schizophrenia risk loci. Nature Neuroscience, 19 (1). pp. 48-54. DOI https://doi.org/10.1038/nn.4182

Malki, Karim and Mineur, Yann S and Tosto, Maria Grazia and Campbell, James and Karia, Priya and Jumabhoy, Irfan and Sluyter, Frans and Crusio, Wim E and Schalkwyk, Leonard C (2015) Pervasive and opposing effects of Unpredictable Chronic Mild Stress (UCMS) on hippocampal gene expression in BALB/cJ and C57BL/6J mouse strains. BMC Genomics, 16 (1). 262-. DOI https://doi.org/10.1186/s12864-015-1431-6

Hannon, Eilis and Lunnon, Katie and Schalkwyk, Leonard and Mill, Jonathan (2015) Interindividual methylomic variation across blood, cortex, and cerebellum: implications for epigenetic studies of neurological and neuropsychiatric phenotypes. Epigenetics, 10 (11). pp. 1024-1032. DOI https://doi.org/10.1080/15592294.2015.1100786

Janecka, M and Manduca, A and Servadio, M and Trezza, V and Smith, R and Mill, J and Schalkwyk, LC and Reichenberg, A and Fernandes, C (2015) Effects of advanced paternal age on trajectories of social behavior in offspring. Genes, Brain and Behavior, 14 (6). pp. 443-453. DOI https://doi.org/10.1111/gbb.12227

Malki, K and Pain, O and Tosto, MG and Du Rietz, E and Carboni, L and Schalkwyk, LC (2015) Identification of genes and gene pathways associated with major depressive disorder by integrative brain analysis of rat and human prefrontal cortex transcriptomes. Translational Psychiatry, 5 (3). e519-e519. DOI https://doi.org/10.1038/tp.2015.15

Spiers, Helen and Hannon, Eilis and Schalkwyk, Leonard C and Smith, Rebecca and Wong, Chloe CY and O’Donovan, Michael C and Bray, Nicholas J and Mill, Jonathan (2015) Methylomic trajectories across human fetal brain development. Genome Research, 25 (3). pp. 338-352. DOI https://doi.org/10.1101/gr.180273.114

Martin, Charlotte and Tansey, Katherine E and Schalkwyk, Leonard C and Powell, Timothy R (2015) The inflammatory cytokines: molecular biomarkers for major depressive disorder? Biomarkers in Medicine, 9 (2). pp. 169-180. DOI https://doi.org/10.2217/bmm.14.29

Boks, Marco P and Mierlo, Hans C van and Rutten, Bart PF and Radstake, Timothy RDJ and De Witte, Lot and Geuze, Elbert and Horvath, Steve and Schalkwyk, Leonard C and Vinkers, Christiaan H and Broen, Jasper CA and Vermetten, Eric (2015) Longitudinal changes of telomere length and epigenetic age related to traumatic stress and post-traumatic stress disorder. Psychoneuroendocrinology, 51. pp. 506-512. DOI https://doi.org/10.1016/j.psyneuen.2014.07.011

Elliott, G and Hong, C and Xing, X and Zhou, X and Li, D and Coarfa, C and Bell, RJA and Maire, CL and Ligon, KL and Sigaroudinia, M and Gascard, P and Tlsty, TD and Harris, RA and Schalkwyk, LC and Bilenky, M and Mill, J and Farnham, PJ and Kellis, M and Marra, MA and Milosavljevic, A and Hirst, M and Stormo, GD and Wang, T and Costello, JF (2015) Intermediate DNA methylation is a conserved signature of genome regulation. Nature Communications, 6 (1). creators-Schalkwyk=3ALeonard_C=3A=3A. DOI https://doi.org/10.1038/ncomms7363

Malki, Karim and Pain, Oliver and Du Rietz, Ebba and Tosto, Maria Grazia and Paya-Cano, Jose and Sandnabba, Kenneth N and de Boer, Sietse and Schalkwyk, Leonard C and Sluyter, Frans (2014) Genes and Gene Networks Implicated in Aggression Related Behaviour. neurogenetics, 15 (4). pp. 255-266. DOI https://doi.org/10.1007/s10048-014-0417-x

Pidsley, R and Viana, J and Hannon, E and Spiers, HH and Troakes, C and Al-Saraj, S and Mechawar, N and Turecki, G and Schalkwyk, LC and Bray, NJ and Mill, J (2014) Methylomic profiling of human brain tissue supports a neurodevelopmental origin for schizophrenia. Genome Biology, 15 (10). creators-Schalkwyk=3ALeonard_C=3A=3A. DOI https://doi.org/10.1186/s13059-014-0483-2

De Jager, Philip L and Srivastava, Gyan and Lunnon, Katie and Burgess, Jeremy and Schalkwyk, Leonard C and Yu, Lei and Eaton, Matthew L and Keenan, Brendan T and Ernst, Jason and McCabe, Cristin and Tang, Anna and Raj, Towfique and Replogle, Joseph and Brodeur, Wendy and Gabriel, Stacey and Chai, High S and Younkin, Curtis and Younkin, Steven G and Zou, Fanggeng and Szyf, Moshe and Epstein, Charles B and Schneider, Julie A and Bernstein, Bradley E and Meissner, Alex and Ertekin-Taner, Nilufer and Chibnik, Lori B and Kellis, Manolis and Mill, Jonathan and Bennett, David A (2014) Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci. Nature Neuroscience, 17 (9). pp. 1156-1163. DOI https://doi.org/10.1038/nn.3786

Lunnon, Katie and Smith, Rebecca and Hannon, Eilis and De Jager, Philip L and Srivastava, Gyan and Volta, Manuela and Troakes, Claire and Al-Sarraj, Safa and Burrage, Joe and Macdonald, Ruby and Condliffe, Daniel and Harries, Lorna W and Katsel, Pavel and Haroutunian, Vahram and Kaminsky, Zachary and Joachim, Catharine and Powell, John and Lovestone, Simon and Bennett, David A and Schalkwyk, Leonard C and Mill, Jonathan (2014) Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease. Nature Neuroscience, 17 (9). pp. 1164-1170. DOI https://doi.org/10.1038/nn.3782

Condliffe, Daniel and Wong, Andrew and Troakes, Claire and Proitsi, Petroula and Patel, Yogen and Chouliaras, Leonidas and Fernandes, Cathy and Cooper, Jonathan and Lovestone, Simon and Schalkwyk, Leonard and Mill, Jonathan and Lunnon, Katie (2014) Cross-region reduction in 5-hydroxymethylcytosine in Alzheimer's disease brain. Neurobiology of Aging, 35 (8). pp. 1850-1854. DOI https://doi.org/10.1016/j.neurobiolaging.2014.02.002

Powell, Timothy R and Powell‐Smith, Georgia and Haddley, Kate and Mcguffin, Peter and Quinn, John and Schalkwyk, Leonard C and Farmer, Anne E and D'Souza, Ursula M (2014) Mood‐stabilizers differentially affect housekeeping gene expression in human cells. International Journal of Methods in Psychiatric Research, 23 (2). pp. 279-288. DOI https://doi.org/10.1002/mpr.1435

Malki, K and Keers, R and Tosto, MG and Lourdusamy, A and Carboni, L and Domenici, E and Uher, R and McGuffin, P and Schalkwyk, LC (2014) The endogenous and reactive depression subtypes revisited: integrative animal and human studies implicate multiple distinct molecular mechanisms underlying major depressive disorder. BMC Medicine, 12 (1). 73-. DOI https://doi.org/10.1186/1741-7015-12-73

Viana, Joana and Pidsley, Ruth and Troakes, Claire and Spiers, Helen and Wong, Chloe CY and Al-Sarraj, Safa and Craig, Ian and Schalkwyk, Leonard and Mill, Jonathan (2014) Epigenomic and transcriptomic signatures of a Klinefelter syndrome (47,XXY) karyotype in the brain. Epigenetics, 9 (4). pp. 587-599. DOI https://doi.org/10.4161/epi.27806

Punapart, M and Eltermaa, M and Oflijan, J and Sütt, S and Must, A and Kõks, S and Schalkwyk, LC and Fernandes, C and Vasar, E and Soomets, U and Terasmaa, A (2014) Effect of chronic valproic Acid treatment on hepatic gene expression profile in wfs1 knockout mouse. PPAR Research, 2014. pp. 1-11. DOI https://doi.org/10.1155/2014/349525

Wong, CCY and Meaburn, EL and Ronald, A and Price, TS and Jeffries, AR and Schalkwyk, LC and Plomin, R and Mill, J (2014) Methylomic analysis of monozygotic twins discordant for autism spectrum disorder and related behavioural traits. Molecular Psychiatry, 19 (4). pp. 495-503. DOI https://doi.org/10.1038/mp.2013.41

Bell, JT and Loomis, AK and Butcher, LM and Gao, F and Zhang, B and Hyde, CL and Sun, J and Wu, H and Ward, K and Harris, J and Scollen, S and Davies, MN and Schalkwyk, LC and Mill, J and Williams, FMK and Li, N and Deloukas, P and Beck, S and McMahon, SB and Wang, J and John, SL and Spector, TD (2014) Differential methylation of the TRPA1 promoter in pain sensitivity. Nature Communications, 5 (1). 2978-. DOI https://doi.org/10.1038/ncomms3978

Tarantino, Lisa M and Schalkwyk, Leonard C (2014) Introduction to mammalian genome special issue: genetics of behavior. Mammalian Genome, 25 (1-2). pp. 1-2. DOI https://doi.org/10.1007/s00335-013-9496-5

Ilott, NE and Schneider, T and Mill, J and Schalkwyk, LC and Brolese, G and Bizarro, L and Stolerman, IP and Dempster, E and Asherson, P (2014) Long-term effects of gestational nicotine exposure and food-restriction on gene expression in the striatum of adolescent rats. PloS One, 9 (2). creators-Schalkwyk=3ALeonard_C=3A=3A. DOI https://doi.org/10.1371/journal.pone.0088896

Powell, TR and McGuffin, P and D'Souza, UM and Cohen-Woods, S and Hosang, GM and Martin, C and Matthews, K and Day, RK and Farmer, AE and Tansey, KE and Schalkwyk, LC (2014) Putative transcriptomic biomarkers in the inflammatory cytokine pathway differentiate major depressive disorder patients from control subjects and bipolar disorder patients. PloS One, 9 (3). creators-Schalkwyk=3ALeonard_C=3A=3A. DOI https://doi.org/10.1371/journal.pone.0091076

Smith, RG and Fernandes, C and Kember, R and Schalkwyk, LC and Buxbaum, J and Reichenberg, A and Mill, J (2014) Transcriptomic changes in the frontal cortex associated with paternal age. Molecular Autism, 5 (1). creators-Schalkwyk=3ALeonard_C=3A=3A. DOI https://doi.org/10.1186/2040-2392-5-24

Davis, OSP and Band, G and Pirinen, M and Haworth, CMA and Meaburn, EL and Kovas, Y and Harlaar, N and Docherty, SJ and Hanscombe, KB and Trzaskowski, M and Curtis, CJC and Strange, A and Freeman, C and Bellenguez, C and Su, Z and Pearson, R and Vukcevic, D and Langford, C and Deloukas, P and Hunt, S and Gray, E and Dronov, S and Potter, SC and Tashakkori-Ghanbaria, A and Edkins, S and Bumpstead, SJ and Blackwell, JM and Bramon, E and Brown, MA and Casas, JP and Corvin, A and Duncanson, A and Jankowski, JAZ and Markus, HS and Mathew, CG and Palmer, CNA and Rautanen, A and Sawcer, SJ and Trembath, RC and Viswanathan, AC and Wood, NW and Barroso, I and Peltonen, L and Dale, PS and Petrill, SA and Schalkwyk, LC and Craig, IW and Lewis, CM and Price, TS and Donnelly, P and Plomin, R and Spencer, CCA (2014) The correlation between reading and mathematics ability at age twelve has a substantial genetic component. Nature Communications, 5 (1). creators-Schalkwyk=3ALeonard_C=3A=3A. DOI https://doi.org/10.1038/ncomms5204

Malki, Karim and Tosto, Maria Grazia and Jumabhoy, Irfan and Lourdusamy, Anbarasu and Sluyter, Frans and Craig, Ian and Uher, Rudolf and McGuffin, Peter and Schalkwyk, Leonard C (2013) Integrative Mouse and Human mRNA Studies Using WGCNA Nominates Novel Candidate Genes Involved in the Pathogenesis of Major Depressive Disorder. Pharmacogenomics, 14 (16). pp. 1979-1990. DOI https://doi.org/10.2217/pgs.13.154

Powell, TR and Smith, RG and Hackinger, S and Schalkwyk, LC and Uher, R and McGuffin, P and Mill, J and Tansey, KE (2013) DNA methylation in interleukin-11 predicts clinical response to antidepressants in GENDEP. Translational Psychiatry, 3 (9). e300-e300. DOI https://doi.org/10.1038/tp.2013.73

Powell, Timothy R and Schalkwyk, Leonard C and Heffernan, Andrew L and Breen, Gerome and Lawrence, Timothy and Price, Tom and Farmer, Anne E and Aitchison, Katherine J and Craig, Ian W and Danese, Andrea and Lewis, Cathryn and McGuffin, Peter and Uher, Rudolf and Tansey, Katherine E and D'Souza, Ursula M (2013) Tumor necrosis factor and its targets in the inflammatory cytokine pathway are identified as putative transcriptomic biomarkers for escitalopram response. European Neuropsychopharmacology, 23 (9). pp. 1105-1114. DOI https://doi.org/10.1016/j.euroneuro.2012.09.009

Powell, Timothy R and Tansey, Katherine E and Breen, Gerome and Farmer, Anne E and Craig, Ian W and Uher, Rudolf and McGuffin, Peter and D’Souza, Ursula M and Schalkwyk, Leonard C (2013) ATP-binding cassette sub-family F member 1 (ABCF1) is identified as a putative therapeutic target of escitalopram in the inflammatory cytokine pathway. Journal of Psychopharmacology, 27 (7). pp. 609-615. DOI https://doi.org/10.1177/0269881113490329

Smith, RG and Reichenberg, A and Kember, RL and Buxbaum, JD and Schalkwyk, LC and Fernandes, C and Mill, J (2013) Advanced paternal age is associated with altered DNA methylation at brain-expressed imprinted loci in inbred mice: implications for neuropsychiatric disease. Molecular Psychiatry, 18 (6). pp. 635-636. DOI https://doi.org/10.1038/mp.2012.88

Pidsley, R and Wong, CCY and Volta, M and Lunnon, K and Mill, J and Schalkwyk, LC (2013) A data-driven approach to preprocessing Illumina 450K methylation array data. BMC Genomics, 14 (1). 293-. DOI https://doi.org/10.1186/1471-2164-14-293

Lill, M and Kõks, S and Soomets, U and Schalkwyk, LC and Fernandes, C and Lutsar, I and Taba, P (2013) Peripheral blood RNA gene expression profiling in patients with bacterial meningitis. Frontiers in Neuroscience, 7 (7). 33-. DOI https://doi.org/10.3389/fnins.2013.00033

Kõks, Sulev and Overall, Rupert W and Ivask, Marilin and Soomets, Ursel and Guha, Mithu and Vasar, Eero and Fernandes, Cathy and Schalkwyk, Leo C (2013) Silencing of the<i>WFS1</i>gene in HEK cells induces pathways related to neurodegeneration and mitochondrial damage. Physiological Genomics, 45 (5). pp. 182-190. DOI https://doi.org/10.1152/physiolgenomics.00122.2012

Navarrete, K and Pedroso, I and De Jong, S and Stefansson, H and Steinberg, S and Stefansson, K and Ophoff, RA and Schalkwyk, LC and Collier, DA (2013) TCF4 (e2-2; ITF2): a schizophrenia-associated gene with pleiotropic effects on human disease. American Journal of Medical Genetics Part B-Neuropsychiatric Genetics, 162 (1). pp. 1-16. DOI https://doi.org/10.1002/ajmg.b.32109

Pidsley, R and Fernandes, C and Viana, J and Paya-Cano, JL and Liu, L and Smith, RG and Schalkwyk, LC and Mill, J (2012) DNA methylation at the Igf2/H19 imprinting control region is associated with cerebellum mass in outbred mice. Molecular Brain, 5 (1). 42-. DOI https://doi.org/10.1186/1756-6606-5-42

Malki, Karim and Lourdusamy, Anbarasu and Binder, Elke and Payá-Cano, Jose and Sluyter, Frans and Craig, Ian and Keers, Robert and McGuffin, Peter and Uher, Rudolf and Schalkwyk, Leonard C (2012) Antidepressant-dependent mRNA changes in mouse associated with hippocampal neurogenesis in a mouse model of depression. Pharmacogenetics and Genomics, 22 (11). pp. 765-776. DOI https://doi.org/10.1097/fpc.0b013e328356fa90

Parsons, MJ and Grimm, C and Paya-Cano, J and Fernandes, C and Liu, L and Philip, VM and Chesler, EJ and Nietfeld, W and Lehrach, H and Schalkwyk, LC (2012) Genetic variation in hippocampal microRNA expression differences in C57BL/6 J X DBA/2 J (BXD) recombinant inbred mouse strains. BMC Genomics, 13 (1). 476-. DOI https://doi.org/10.1186/1471-2164-13-476

Jeffries, Aaron R and Perfect, Leo W and Ledderose, Julia and Schalkwyk, Leonard C and Bray, Nicholas J and Mill, Jonathan and Price, Jack (2012) Stochastic Choice of Allelic Expression in Human Neural Stem Cells. Stem Cells, 30 (9). pp. 1938-1947. DOI https://doi.org/10.1002/stem.1155

Malki, Karim and Campbell, James and Davies, Matthew and Keers, Robert and Uher, Rudolf and Ward, Malcolm and Paya‐Cano, Jose and Aitchinson, Katherine J and Binder, Elke and Sluyter, Frans and Kuhn, Karsten and Selzer, Stefan and Craig, Ian and McGuffin, Peter and Schalkwyk, Leonard C (2012) Pharmacoproteomic investigation into antidepressant response in two mouse inbred strains. PROTEOMICS, 12 (14). pp. 2355-2365. DOI https://doi.org/10.1002/pmic.201100306

Kember, RL and Dempster, EL and Lee, THA and Schalkwyk, LC and Mill, J and Fernandes, C (2012) Maternal separation is associated with strain‐specific responses to stress and epigenetic alterations to <i>Nr3c1</i>,<i> Avp</i>, and <i>Nr4a1</i> in mouse. Brain and Behavior, 2 (4). pp. 455-467. DOI https://doi.org/10.1002/brb3.69

Davies, MN and Volta, M and Pidsley, R and Lunnon, K and Dixit, A and Lovestone, S and Coarfa, C and Harris, RA and Milosavljevic, A and Troakes, C and Al-Sarraj, S and Dobson, R and Schalkwyk, LC and Mill, J (2012) Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood. Genome Biology, 13 (6). R43-. DOI https://doi.org/10.1186/gb-2012-13-6-r43

Keers, R and Pedroso, I and Breen, G and Aitchison, KJ and Nolan, PM and Cichon, S and Nothen, MM and Rietschel, M and Schalkwyk, LC and Fernandes, C (2012) Reduced Anxiety and Depression-Like Behaviours in the Circadian Period Mutant Mouse Afterhours. PloS One, 7 (6). creators-Schalkwyk=3ALeonard_C=3A=3A. DOI https://doi.org/10.1371/journal.pone.0038263

Dempster, Emma L and Pidsley, Ruth and Schalkwyk, Leonard C and Owens, Sheena and Georgiades, Anna and Kane, Fergus and Kalidindi, Sridevi and Picchioni, Marco and Kravariti, Eugenia and Toulopoulou, Timothea and Murray, Robin M and Mill, Jonathan (2011) Disease-associated epigenetic changes in monozygotic twins discordant for schizophrenia and bipolar disorder. Human Molecular Genetics, 20 (24). pp. 4786-4796. DOI https://doi.org/10.1093/hmg/ddr416

Binder, Elke and Malki, Karim and Paya-Cano, Jose L and Fernandes, Cathy and Aitchison, Katherine J and Mathé, Aleksander A and Sluyter, Frans and Schalkwyk, Leonard C (2011) Antidepressants and the resilience to early-life stress in inbred mouse strains. Pharmacogenetics and Genomics, 21 (12). pp. 779-789. DOI https://doi.org/10.1097/fpc.0b013e32834b3f35

Kõks, Sulev and Soomets, Ursel and Plaas, Mario and Terasmaa, Anton and Noormets, Klari and Tillmann, Vallo and Vasar, Eero and Fernandes, Cathy and Schalkwyk, Leonard C (2011) Hypothalamic gene expression profile indicates a reduction in G protein signaling in the<i>Wfs1</i>mutant mice. Physiological Genomics, 43 (24). pp. 1351-1358. DOI https://doi.org/10.1152/physiolgenomics.00117.2011

Malki, Karim and Uher, Rudolf and Paya-Cano, Jose and Binder, Elke and Rietschel, Marcella and Zobel, Astrid and Mors, Ole and Hauser, Joanna and Henigsberg, Neven and Jerman, Borut and Souery, Daniel and Placentino, Anna and Ng, Mandy Y and Cohen-Woods, Sarah and Sluyter, Frans and Farmer, Anne and Aitchison, Katherine J and Craig, Ian W and Lewis, Cathryn M and McGuffin, Peter and Schalkwyk, Leonard C (2011) Convergent Animal and Human Evidence Suggests a Role of PPM1A Gene in Response to Antidepressants. Biological Psychiatry, 69 (4). pp. 360-365. DOI https://doi.org/10.1016/j.biopsych.2010.08.011

Davies, MN and Meaburn, EL and Schalkwyk, LC (2010) Gene set enrichment; a problem of pathways. Briefings in Functional Genomics, 9 (5-6). pp. 385-390. DOI https://doi.org/10.1093/bfgp/elq021

Kember, RL and Fernandes, C and Tunbridge, EM and Liu, L and Payá‐Cano, JL and Parsons, MJ and Schalkwyk, LC (2010) A B2 SINE insertion in the <i>Comt1</i> gene (<i>Comt1</i>^<i>B2i</i>) results in an overexpressing, behavior modifying allele present in classical inbred mouse strains. Genes, Brain and Behavior, 9 (8). pp. 925-932. DOI https://doi.org/10.1111/j.1601-183x.2010.00614.x

Davis, Oliver SP and Butcher, Lee M and Docherty, Sophia J and Meaburn, Emma L and Curtis, Charles JC and Simpson, Michael A and Schalkwyk, Leonard C and Plomin, Robert (2010) A Three-Stage Genome-Wide Association Study of General Cognitive Ability: Hunting the Small Effects. Behavior Genetics, 40 (6). pp. 759-767. DOI https://doi.org/10.1007/s10519-010-9350-4

Meaburn, Emma L and Schalkwyk, Leonard C and Mill, Jonathan (2010) Allele-specific methylation in the human genome. Epigenetics, 5 (7). pp. 578-582. DOI https://doi.org/10.4161/epi.5.7.12960

Kõks, S and Velthut, A and Sarapik, A and Altmäe, S and Reinmaa, E and Schalkwyk, LC and Fernandes, C and Lad, HV and Soomets, U and Jaakma, Ü and Salumets, A (2010) The differential transcriptome and ontology profiles of floating and cumulus granulosa cells in stimulated human antral follicles. MHR: Basic science of reproductive medicine, 16 (4). pp. 229-240. DOI https://doi.org/10.1093/molehr/gap103

Lad, Heena Vanmalibhai and Liu, Lin and Paya-Cano, Jose Luis and Parsons, Michael James and Kember, Rachel and Fernandes, Cathy and Schalkwyk, Leonard Cornelis (2010) Behavioural battery testing: Evaluation and behavioural outcomes in 8 inbred mouse strains. Physiology &amp; Behavior, 99 (3). pp. 301-316. DOI https://doi.org/10.1016/j.physbeh.2009.11.007

Docherty, SJ and Davis, OSP and Kovas, Y and Meaburn, EL and Dale, PS and Petrill, SA and Schalkwyk, LC and Plomin, R (2010) A genome‐wide association study identifies multiple loci associated with mathematics ability and disability. Genes, Brain and Behavior, 9 (2). pp. 234-247. DOI https://doi.org/10.1111/j.1601-183x.2009.00553.x

Schalkwyk, Leonard C and Meaburn, Emma L and Smith, Rebecca and Dempster, Emma L and Jeffries, Aaron R and Davies, Matthew N and Plomin, Robert and Mill, Jonathan (2010) Allelic Skewing of DNA Methylation Is Widespread across the Genome. The American Journal of Human Genetics, 86 (2). pp. 196-212. DOI https://doi.org/10.1016/j.ajhg.2010.01.014

Ronald, Angelica and Butcher, Lee M and Docherty, Sophia and Davis, Oliver SP and Schalkwyk, Leonard C and Craig, Ian W and Plomin, Robert (2010) A Genome-Wide Association Study of Social and Non-Social Autistic-Like Traits in the General Population Using Pooled DNA, 500 K SNP Microarrays and Both Community and Diagnosed Autism Replication Samples. Behavior Genetics, 40 (1). pp. 31-45. DOI https://doi.org/10.1007/s10519-009-9308-6

Ronald, Angelica and Butcher, Lee M and Docherty, Sophia J and Davis, Oliver SP and Schalkwyk, Leonard C and Craig, Ian W and Plomin, Robert (2010) Response to comment by Stuart Macgregor. Behavior Genetics, 40 (1). p. 48. DOI https://doi.org/10.1007/s10519-009-9319-3

Smith, Rebecca G and Kember, Rachel L and Mill, Jonathan and Fernandes, Cathy and Schalkwyk, Leonard C and Buxbaum, Joseph D and Reichenberg, Abraham (2009) Advancing Paternal Age Is Associated with Deficits in Social and Exploratory Behaviors in the Offspring: A Mouse Model. PLoS ONE, 4 (12). e8456-e8456. DOI https://doi.org/10.1371/journal.pone.0008456

Davies, Matthew N and Lawn, Sarah and Whatley, Steven and Fernandes, Cathy and Williams, Robert W and Schalkwyk, Leonard C (2009) To What Extent is Blood a Reasonable Surrogate for Brain in Gene Expression Studies: Estimation from Mouse Hippocampus and Spleen. Frontiers in Neuroscience, 3 (OCT). 54-. DOI https://doi.org/10.3389/neuro.15.002.2009

Meaburn, EL and Fernandes, C and Craig, IW and Plomin, R and Schalkwyk, LC (2009) Assessing Individual Differences in Genome-Wide Gene Expression in Human Whole Blood: Reliability Over Four Hours and Stability Over 10 Months. Twin Research and Human Genetics, 12 (4). pp. 372-380. DOI https://doi.org/10.1375/twin.12.4.372

Kõks, S and Soomets, U and Paya-Cano, JL and Fernandes, C and Luuk, H and Plaas, M and Terasmaa, A and Tillmann, V and Noormets, K and Vasar, E and Schalkwyk, LC (2009) Wfs1 gene deletion causes growth retardation in mice and interferes with the growth hormone pathway. Physiological Genomics, 37 (3). pp. 249-259. DOI https://doi.org/10.1152/physiolgenomics.90407.2008

Davis, Oliver SP and Plomin, Robert and Schalkwyk, Leonard C (2009) The SNPMaP package for R: a framework for genome-wide association using DNA pooling on microarrays. Bioinformatics, 25 (2). pp. 281-283. DOI https://doi.org/10.1093/bioinformatics/btn587

Kas, MJH and Gelegen, C and Schalkwyk, LC and Collier, DA (2009) Interspecies Comparisons of Functional Genetic Variations and Their Implications in Neuropsychiatry. American Journal of Medical Genetics Part B-Neuropsychiatric Genetics, 150B (3). pp. 309-317. DOI https://doi.org/10.1002/ajmg.b.30815

Parsons, Michael J and Grimm, Christina H and Paya-Cano, Jose L and Sugden, Karen and Nietfeld, Wilfried and Lehrach, Hans and Schalkwyk, Leonard C (2008) Using hippocampal microRNA expression differences between mouse inbred strains to characterise miRNA function. Mammalian Genome, 19 (7-8). pp. 552-560. DOI https://doi.org/10.1007/s00335-008-9116-y

Meaburn, EL and Harlaar, N and Craig, IW and Schalkwyk, LC and Plomin, R (2008) Quantitative trait locus association scan of early reading disability and ability using pooled DNA and 100K SNP microarrays in a sample of 5760 children. Molecular Psychiatry, 13 (7). pp. 729-740. DOI https://doi.org/10.1038/sj.mp.4002063

Kõks, Sulev and Fernandes, Cathy and Kurrikoff, Kaido and Vasar, Eero and Schalkwyk, Leonard C (2008) Gene expression profiling reveals upregulation of Tlr4 receptors in Cckb receptor deficient mice. Behavioural Brain Research, 188 (1). pp. 62-70. DOI https://doi.org/10.1016/j.bbr.2007.10.020

Caspi, Avshalom and Williams, Benjamin and Kim-Cohen, Julia and Craig, Ian W and Milne, Barry J and Poulton, Richie and Schalkwyk, Leonard C and Taylor, Alan and Werts, Helen and Moffitt, Terrie E (2007) Moderation of breastfeeding effects on the IQ by genetic variation in fatty acid metabolism. Proceedings of the National Academy of Sciences, 104 (47). pp. 18860-18865. DOI https://doi.org/10.1073/pnas.0704292104

Docherty, SJ and Butcher, LM and Schalkwyk, LC and Plomin, R (2007) Applicability of DNA pools on 500 KSNP microarrays for cost-effective initial screens in genomewide association studies. BMC Genomics, 8 (1). p. 214. DOI https://doi.org/10.1186/1471-2164-8-214

Lad, Heena V and Liu, Lin and Payá-Cano, José L and Fernandes, Cathy and Schalkwyk, Leonard C (2007) Quantitative traits for the tail suspension test: automation, optimization, and BXD RI mapping. Mammalian Genome, 18 (6-7). pp. 482-491. DOI https://doi.org/10.1007/s00335-007-9029-1

Kas, MJH and Fernandes, C and Schalkwyk, LC and Collier, DA (2007) Genetics of behavioural domains across the neuropsychiatric spectrum; of mice and men. Molecular Psychiatry, 12 (4). pp. 324-330. DOI https://doi.org/10.1038/sj.mp.4001979

Schalkwyk, LC and Fernandes, C and Nash, MW and Kurrikoff, K and Vasar, E and Kõks, S (2007) Interpretation of knockout experiments: the congenic footprint. Genes, Brain and Behavior, 6 (3). pp. 299-303. DOI https://doi.org/10.1111/j.1601-183x.2007.00304.x

Sugden, K and D'Souza, UM and Aitchison, KJ and Schalkwyk, LC and McGuffin, P and Byers, H and Campbell, J and Hye, A and Pariante, CM (2007) P.1.31 Gene expression analyses of mouse fibroblast cell line L929 after antidepressant treatment. European Neuropsychopharmacology, 17. S27-S28. DOI https://doi.org/10.1016/s0924-977x(07)70032-9

Plomin, Robert and Schalkwyk, Leonard C (2007) Microarrays. Developmental Science, 10 (1). pp. 19-23. DOI https://doi.org/10.1111/j.1467-7687.2007.00558.x

Fernandes, C and Hoyle, E and Dempster, E and Schalkwyk, LC and Collier, DA (2006) Performance deficit of α7 nicotinic receptor knockout mice in a delayed matching‐to‐place task suggests a mild impairment of working/episodic‐like memory. Genes, Brain and Behavior, 5 (6). pp. 433-440. DOI https://doi.org/10.1111/j.1601-183x.2005.00176.x

D'Souza, U and Sugden, K and Aitchison, KJ and Schalkwyk, LC and McGuffin, P and Pariante, M (2006) S.16.02 Depression: the GENDEP study. European Neuropsychopharmacology, 16. S187-S187. DOI https://doi.org/10.1016/s0924-977x(06)70079-7

Meaburn, EL and Butcher, LM and Schalkwyk, LC and Plomin, R (2006) Genotyping pooled DNA using 100K SNP microarrays: a step towards genomewide association scans. Nucleic acids research, 34 (4). creators-Schalkwyk=3ALeonard_C=3A=3A. DOI https://doi.org/10.1093/nar/gnj027

Galsworthy, Michael J and Paya-Cano, Jose L and Liu, Lin and Monleón, Santiago and Gregoryan, Gregory and Fernandes, Cathy and Schalkwyk, Leonard C and Plomin, Robert (2005) Assessing Reliability, Heritability and General Cognitive Ability in a Battery of Cognitive Tasks for Laboratory Mice. Behavior Genetics, 35 (5). pp. 675-692. DOI https://doi.org/10.1007/s10519-005-3423-9

Butcher, Lee M and Meaburn, Emma and Knight, Jo and Sham, Pak C and Schalkwyk, Leonard C and Craig, Ian W and Plomin, Robert (2005) SNPs, microarrays and pooled DNA: identification of four loci associated with mild mental impairment in a sample of 6000 children. Human Molecular Genetics, 14 (10). pp. 1315-1325. DOI https://doi.org/10.1093/hmg/ddi142

Butcher, LM and Meaburn, E and Dale, PS and Sham, P and Schalkwyk, LC and Craig, IW and Plomin, R (2005) Association analysis of mild mental impairment using DNA pooling to screen 432 brain-expressed single-nucleotide polymorphisms. Molecular Psychiatry, 10 (4). pp. 384-392. DOI https://doi.org/10.1038/sj.mp.4001589

Meaburn, EL and Butcher, LM and Liu, L and Fernandes, C and Hansen, V and Al-Chalabi, A and Plomin, R and Craig, IW and Schalkwyk, LC (2005) Genotyping DNA pools on microarrays: Tackling the QTL problem of large samples and large numbers of SNPs. BMC Genomics, 6 (1). creators-Schalkwyk=3ALeonard_C=3A=3A. DOI https://doi.org/10.1186/1471-2164-6-52

Simpson, CL and Knight, J and Butcher, LM and Hansen, VK and Meaburn, EL and Schalkwyk, LC and Craig, IW and Powell, JF and Sham, PC and Al-Chalabi, A (2005) A central resource for accurate allele frequency estimation from pooled DNA genotyped on DNA microarrays. Nucleic Acids Research, 33 (3). e25-e25. DOI https://doi.org/10.1093/nar/gni028

Fernandes, Cathy and Liu, Lin and Paya-Cano, Jos L and Gregorov�, So A and Forejt, Ji and Schalkwyk, Leonard C (2004) Behavioral Characterization of Wild Derived Male Mice (Mus musculus musculus) of the PWD/Ph Inbred Strain: High Exploration Compared to C57BL/6J. Behavior Genetics, 34 (6). pp. 621-630. DOI https://doi.org/10.1007/s10519-004-5589-y

Churchill, GA and Airey, DC and Allayee, H and Angel, JM and Attie, AD and Beatty, J and Beavis, WD and Belknap, JK and Bennett, B and Berrettini, W and Bleich, A and Bogue, M and Broman, KW and Buck, KJ and Buckler, E and Burmeister, M and Chesler, EJ and Cheverud, JM and Clapcote, S and Cook, MN and Cox, RD and Crabbe, JC and Crusio, WE and Darvasi, A and Deschepper, CF and Doerge, RW and Farber, CR and Forejt, J and Gaile, D and Garlow, SJ and Geiger, H and Gershenfeld, H and Gordon, T and Gu, J and Gu, W and de Haan, G and Hayes, NL and Heller, C and Himmelbauer, H and Hitzemann, R and Hunter, K and Hsu, HC and Iraqi, FA and Ivandic, B and Jacob, HJ and Jansen, RC and Jepsen, KJ and Johnson, DK and Johnson, TE and Kempermann, G and Kendziorski, C and Kotb, M and Kooy, RF and Llamas, B and Lammert, F and Lassalle, JM and Lowenstein, PR and Lu, L and Lusis, A and Manly, KF and Marcucio, R and Matthews, D and Medrano, JF and Miller, DR and Mittleman, G and Mock, BA and Mogil, JS and Montagutelli, X and Morahan, G and Morris, DG and Mott, R and Nadeau, JH and Nagase, H and Nowakowski, RS and O'Hara, BF and Osadchuk, AV and Page, GP and Paigen, B and Paigen, K and Palmer, AA and Pan, HJ and Peltonen-Palotie, L and Peirce, J and Pomp, D and Pravenec, M and Prows, DR and Qi, Z and Reeves, RH and Roder, J and Rosen, GD and Schadt, EE and Schalkwyk, LC and Seltzer, Z and Shimomura, K and Shou, S and Sillanpää, MJ and Siracusa, LD and Snoeck, HW and Spearow, JL and Svenson, K (2004) The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nature Genetics, 36 (11). pp. 1133-1137. DOI https://doi.org/10.1038/ng1104-1133

Butcher, Lee M and Meaburn, Emma and Liu, Lin and Fernandes, Cathy and Hill, Linzy and Al-Chalabi, Ammar and Plomin, Robert and Schalkwyk, Leo and Craig, Ian W (2004) Genotyping Pooled DNA on Microarrays: A Systematic Genome Screen of Thousands of SNPs in Large Samples to Detect QTLs for Complex Traits. Behavior Genetics, 34 (5). pp. 549-555. DOI https://doi.org/10.1023/b:bege.0000038493.26202.d3

Craig, Ian W and Mill, Jonathan and Craig, Gavin M and Loat, Caroline and Schalkwyk, Leonard C (2004) Application of microarrays to the analysis of the inactivation status of human X-linked genes expressed in lymphocytes. European Journal of Human Genetics, 12 (8). pp. 639-646. DOI https://doi.org/10.1038/sj.ejhg.5201212

Ben Abdelkhalek, Hanaa and Beckers, Anja and Schuster-Gossler, Karin and Pavlova, Maria N and Burkhardt, Hannelore and Lickert, Heiko and Rossant, Janet and Reinhardt, Richard and Schalkwyk, Leonard C and Müller, Ines and Herrmann, Bernhard G and Ceolin, Marcelo and Rivera-Pomar, Rolando and Gossler, Achim (2004) The mouse homeobox gene <i>Not</i> is required for caudal notochord development and affected by the truncate mutation. Genes &amp; Development, 18 (14). pp. 1725-1736. DOI https://doi.org/10.1101/gad.303504

Fernandes, Cathy and Paya‐Cano, Jose L and Sluyter, Frans and D'Souza, Ursula and Plomin, Robert and Schalkwyk, Leonard C (2004) Hippocampal gene expression profiling across eight mouse inbred strains: towards understanding the molecular basis for behaviour. European Journal of Neuroscience, 19 (9). pp. 2576-2582. DOI https://doi.org/10.1111/j.0953-816x.2004.03358.x

Nyberg, J and Sandnabba, K and Schalkwyk, L and Sluyter, F (2004) Genetic and environmental (inter)actions in male mouse lines selected for aggressive and nonaggressive behavior. Genes, Brain and Behavior, 3 (2). pp. 101-109. DOI https://doi.org/10.1111/j.1601-183x.2003.0056.x

Stolerman, IP and Chamberlain, S and Bizarro, L and Fernandes, C and Schalkwyk, L (2004) The role of nicotinic receptor α7 subunits in nicotine discrimination. Neuropharmacology, 46 (3). pp. 363-371. DOI https://doi.org/10.1016/j.neuropharm.2003.10.002

Abiola, O and Angel, JM and Avner, P and Bachmanov, AA and Belknap, JK and Bennett, B and Blankenhorn, EP and Blizard, DA and Bolivar, V and Brockmann, GA and Buck, KJ and Bureau, JF and Casley, WL and Chesler, EJ and Cheverud, JM and Churchill, GA and Cook, M and Crabbe, JC and Crusio, WE and Darvasi, A and de Haan, G and Demant, P and Doerge, RW and Elliott, RW and Farber, CR and Flaherty, L and Flint, J and Gershenfeld, H and Gibson, JP and Gu, J and Gu, W and Himmelbauer, H and Hitzemann, R and Hsu, HC and Hunter, K and Iraqi, FA and Jansen, RC and Johnson, TE and Jones, BC and Kempermann, G and Lammert, F and Lu, L and Manly, KF and Matthews, DB and Medrano, JF and Mehrabian, M and Mittleman, G and Mock, BA and Mogil, JS and Montagutelli, X and Morahan, G and Mountz, JD and Nagase, H and Nowakowski, RS and O'Hara, BF and Osadchuk, AV and Paigen, B and Palmer, AA and Peirce, JL and Pomp, D and Rosemann, M and Rosen, GD and Schalkwyk, LC and Seltzer, Z and Settle, S and Shimomura, K and Shou, S and Sikela, JM and Siracusa, LD and Spearow, JL and Teuscher, C and Threadgill, DW and Toth, LA and Toye, AA and Vadasz, C and Van Zant, G and Wakeland, E and Williams, RW and Zhang, HG and Zou, F (2003) The nature and identification of quantitative trait loci: a community's view. Nature Reviews Genetics, 4 (11). pp. 911-916. DOI https://doi.org/10.1038/nrg1206

Sluyter, Frans and Schalkwyk, Leonard C (2003) Aggression across species. Behavior Genetics, 33 (5). pp. 457-460. DOI https://doi.org/10.1023/a:1025744430180

Mill, J and Galsworthy, MJ and Paya‐Cano, JL and Sluyter, F and Schalkwyk, LC and Plomin, R and Asherson, P (2002) Home‐cage activity in heterogeneous stock (HS) mice as a model of baseline activity. Genes, Brain and Behavior, 1 (3). pp. 166-173. DOI https://doi.org/10.1034/j.1601-183x.2002.10304.x

Klose, Joachim and Nock, Christina and Herrmann, Marion and Stühler, Kai and Marcus, Katrin and Blüggel, Martin and Krause, Eberhard and Schalkwyk, Leonard C and Rastan, Sohaila and Brown, Steve DM and Büssow, Konrad and Himmelbauer, Heinz and Lehrach, Hans (2002) Genetic analysis of the mouse brain proteome. Nature Genetics, 30 (4). pp. 385-393. DOI https://doi.org/10.1038/ng861

Schalkwyk, Leonard C and Cusack, Brian and Dunkel, Ilona and Hopp, Martina and Kramer, Markus and Palczewski, Stefanie and Piefke, Jutta and Scheel, Sabine and Weiher, Michael and Wenske, Gunther and Lehrach, Hans and Himmelbauer, Heinz (2001) Advanced Integrated Mouse YAC Map Including BAC Framework. Genome Research, 11 (12). pp. 2142-2150. DOI https://doi.org/10.1101/gr.176201

Gösele, Claudia and Hong, Liu and Kreitler, Thomas and Rossmann, Marlies and Hieke, Brigitte and Groß, Uwe and Kramer, Markus and Himmelbauer, Heinz and Bihoreau, Marie-Thérese and Kwitek-Black, Anne E and Twigger, Simon and Tonellato, Peter J and Jacob, Howard J and Schalkwyk, Leonard C and Lindpaintner, Klaus and Ganten, Detlev and Lehrach, Hans and Knoblauch, Margit (2000) High-Throughput Scanning of the Rat Genome Using Interspersed Repetitive Sequence-PCR Markers. Genomics, 69 (3). pp. 287-294. DOI https://doi.org/10.1006/geno.2000.6352

Knoblauch, M and Gösele, C and Zimdahl, H and Hieke, B and Himmelbauer, H and Schalkwyk, L and Lindpaintner, K and Ganten, D and Lehrach, H (2000) New tools for the high throughput characterization of rat genomic DNA samples. Journal of Experimental Animal Science, 41 (1-2). pp. 35-37. DOI https://doi.org/10.1016/s0939-8600(00)80024-3

Leong, Wey L and Dobson, Melanie J and Logsdon, Jr., John M and Abdel-Majid, Raja M and Schalkwyk, Leonard C and Guernsey, Duane L and Neumann, Paul E (2000) ETn insertion in the mouse Adcy1 gene: transcriptional and phylogenetic analyses. Mammalian Genome, 11 (2). pp. 97-103. DOI https://doi.org/10.1007/s003350010020

Schalkwyk, LC and Himmelbauer, H and Lehrach, H (1999) Toward the mammalian transcript map. Archiv fur Tierzucht, 42 (6 SUPP). pp. 67-73.

Schalkwyk, Leonard C and Jung, Martin and Daser, Angelika and Weiher, Michael and Walter, Jörn and Himmelbauer, Heinz and Lehrach, Hans (1999) Panel of Microsatellite Markers for Whole-Genome Scans and Radiation Hybrid Mapping and a Mouse Family Tree. Genome Research, 9 (9). pp. 878-887. DOI https://doi.org/10.1101/gr.9.9.878

Hills, David and Tracey, Simon and Masabanda, Julio and Fries, Ruedi and Schalkwyk, Leonard C and Lehrach, Hans and Miller, J Ross and Williams, John L (1999) A bovine YAC library containing four- to five-fold genome equivalents. Mammalian Genome, 10 (8). pp. 837-838. DOI https://doi.org/10.1007/s003359901100

Zhu, Baoli and Smith, Judith A and Tracey, Simon M and Konfortov, Bernard A and Welzel, Katrin and Schalkwyk, Leonard C and Lehrach, Hans and Kollers, Sonja and Masabanda, Julio and Buitkamp, Johannes and Fries, Ruedi and Williams, John L and Miller, J Ross (1999) A 5× genome coverage bovine BAC library: production, characterization, and distribution. Mammalian Genome, 10 (7). pp. 706-709. DOI https://doi.org/10.1007/s003359901075

Nock, Christina and Gauss, Christine and Schalkwyk, Leonard C and Klose, Joachim and Lehrach, Hans and Himmelbauer, Heinz (1999) Technology development at the interface of proteome research and genomics: Mapping nonpolymorphic proteins on the physical map of mouse chromosomes. Electrophoresis, 20 (4-5). pp. 1027-1032. DOI https://doi.org/10.1002/(sici)1522-2683(19990101)20:4/5<1027::aid-elps1027>3.0.co;2-i

Schalkwyk, Leonard C and Weiher, Michael and Kirby, Michelle and Cusack, Brian and Himmelbauer, Heinz and Lehrach, Hans (1998) Refined radiation hybrid map of mouse Chromosome 17. Mammalian Genome, 9 (10). pp. 807-811. DOI https://doi.org/10.1007/s003359900871

Himmelbauer, H and Dunkel, I and Otto, GW and Burgtorf, C and Schalkwyk, LC and Lehrach, H (1998) Complex probes for high-throughput parallel genetic mapping of genomic mouse BAC clones. Mammalian Genome, 9 (8). pp. 611-616. DOI https://doi.org/10.1007/s003359900831

Buitkamp, J and Ewald, D and Schalkwyk, L and Weiher, M and Masabanda, J and Sazanov, A and Lehrach, H and Fries, R (1998) Construction and characterisation of a gridded chicken cosmid library with four‐fold genomic coverage. Animal Genetics, 29 (4). pp. 295-301. DOI https://doi.org/10.1046/j.1365-2052.1998.00331.x

Abdel-Majid, Raja M and Leong, Wey L and Schalkwyk, Leonard C and Smallman, Donald S and Wong, Scott T and Storm, Daniel R and Fine, Alan and Dobson, Melanie J and Guernsey, Duane L and Neumann, Paul E (1998) Loss of adenylyl cyclase I activity disrupts patterning of mouse somatosensory cortex. Nature Genetics, 19 (3). pp. 289-291. DOI https://doi.org/10.1038/980

Himmelbauer, Heinz and Wedemeyer, Niels and Haaf, Thomas and Wanker, Erich E and Schalkwyk, Leonard C and Lehrach, Hans (1998) IRS-PCR-based genetic mapping of the huntingtin interacting protein gene (HIP1) on mouse Chromosome 5. Mammalian Genome, 9 (1). pp. 26-31. DOI https://doi.org/10.1007/s003359900674

Crnogorac-Jurcevic, T and Brown, JR and Lehrach, H and Schalkwyk, LC (1997) Tetraodon fluviatilis,a New Puffer Fish Model for Genome Studies. Genomics, 41 (2). pp. 177-184. DOI https://doi.org/10.1006/geno.1997.4646

Toye, Ayo A and Schalkwyk, Leonard and Lehrach, Hans and Bumstead, Nat (1997) A yeast artificial chromosome (YAC) library containing 10 haploid chicken genome equivalents. Mammalian Genome, 8 (4). pp. 274-276. DOI https://doi.org/10.1007/s003359900408

Cai, Li and Schalkwyk, Leonard C and Schoeberlein-Stehli, Andreina and Zee, Robert YL and Smith, Avrial and Haaf, Thomas and Georges, Michel and Lehrach, Hans and Lindpaintner, Klaus (1997) Construction and Characterization of a 10-Genome Equivalent Yeast Artificial Chromosome Library for the Laboratory Rat,Rattus norvegicus. Genomics, 39 (3). pp. 385-392. DOI https://doi.org/10.1006/geno.1996.4494

Hunter, KW and Riba, L and Schalkwyk, L and Clark, M and Resenchuk, S and Beeghly, A and Su, J and Tinkov, F and Lee, P and Ramu, E and Lehrach, H and Housman, D (1996) Toward the construction of integrated physical and genetic maps of the mouse genome using interspersed repetitive sequence PCR (IRS-PCR) genomics. Genome Research, 6 (4). pp. 290-299. DOI https://doi.org/10.1101/gr.6.4.290

McCarthy, L and Hunter, K and Schalkwyk, L and Riba, L and Anson, S and Mott, R and Newell, W and Bruley, C and Bar, I and Ramu, E (1995) Efficient high-resolution genetic mapping of mouse interspersed repetitive sequence PCR products, toward integrated genetic and physical mapping of the mouse genome. Proceedings of the National Academy of Sciences, 92 (12). pp. 5302-5306. DOI https://doi.org/10.1073/pnas.92.12.5302

Breen, M and Deakln, L and Macdonald, B and Miller, S and Sibson, R and Tarttelln, E and Avner, P and Bourgade, F and Guenet, JL and Montagutelli, X and Polrier, C and Simon, D and Tailor, D and Bishop, M and Kelly, M and Rysavy, F and Rastan, S and Norris, D and Shepherd, D and Abbott, C and Pllz, A and Hodge, S and Jackson, I and Boyd, Y and Blair, H and Maslen, G and A.todd, J and W.reed, P and Stoye, J and Ashworth, A and Mccarthy, L and Cox, R and Schalkwyk, L and Lehrach, H and Klose, J and Gangadharan, U and Brown, S (1994) Towards high resolution maps of the mouse and human genomes - a facility for ordering markers to 0.1 cm resolution. Human Molecular Genetics, 3 (4). 621 - 627. DOI https://doi.org/10.1093/hmg/3.4.621

Breen, M and Deakin, L and Macdonald, B and Miller, S and Sibson, R and Tarttelin, E and Avner, P and Bourgade, F and Guenet, JL and Montagutelli, X and Poirier, C and Simon, D and Tailor, D and Bishop, M and Kelly, M and Rysavy, F and Rastan, S and Norris, D and Shepherd, D and Abbott, C and Pilz, A and Hodge, S and Jackson, I and Boyd, Y and Blair, H and Maslen, G and Todd, JA and Reed, PW and Stoye, J and Ashworth, A and McCarthy, L and Cox, R and Schalkwyk, LC and Lehrach, H and Klose, J and Gangadharan, U and Brown, S (1994) Towards high resolution maps of the mouse and human genomes?a facility for ordering markers to 0.1 cM resolution. Human Molecular Genetics, 3 (4). pp. 621-627. DOI https://doi.org/10.1093/hmg/3.4.621

A.Jones, Karen and M.Black, Donald and A.Brown, Melissa and L.Griffiths, Beatrice and M.Nicolai, Hans and A.Chambers, Julie and Bonjardim, Marisa and Xu, Chun-Fang and Boyd, Marie and MeFariane, Robert and Korn, Bernhard and Poustka, Annemarie and A.North, Michael and Schalkwyk, Leo and Lehrach, Hans and Solomon, Ellen (1994) The detailed characterisation of a 400 kb cosmid walk in the <i>BRCA1</i> region: identification and localisation of 10 genes including a dual-specificity phosphatase. Human Molecular Genetics, 3 (11). pp. 1927-1934. DOI https://doi.org/10.1093/hmg/3.11.1927

Schalkwyk, Leonard C and Charlebois, Robert L and Doolittle, W Ford (1993) Insertion sequences on plasmid pHV1 of <i>Haloferax volcanii</i>. Canadian Journal of Microbiology, 39 (2). pp. 201-206. DOI https://doi.org/10.1139/m93-028

Cohen, A and Lam, WL and Charlebois, RL and Doolittle, WF and Schalkwyk, LC (1992) Localizing genes on the map of the genome of Haloferax volcanii, one of the Archaea. Proceedings of the National Academy of Sciences, 89 (5). pp. 1602-1606. DOI https://doi.org/10.1073/pnas.89.5.1602

Doolittle, WF and Lam, WL and Schalkwyk, LC and Charlebois, RL and Cline, SW and Cohen, A (1992) Progress in developing the genetics of the halobacteria. Biochemical Society symposium, 58 (58). pp. 73-78.

Charlebois, Robert L and Schalkwyk, Leonard C and Hofman, Jason D and Doolittle, W Ford (1991) Detailed physical map and set of overlapping clones covering the genome of the archaebacterium Haloferax volcanii DS2. Journal of Molecular Biology, 222 (3). pp. 509-524. DOI https://doi.org/10.1016/0022-2836(91)90493-p

Cline, SW and Schalkwyk, LC and Doolittle, WF (1989) Transformation of the archaebacterium Halobacterium volcanii with genomic DNA. Journal of Bacteriology, 171 (9). pp. 4987-4991. DOI https://doi.org/10.1128/jb.171.9.4987-4991.1989

Charlebois, Robert L and Hofman, Jason D and Schalkwyk, Leonard C and Lam, Wan L and Doolittle, W Ford (1989) Genome mapping in halobacteria. Canadian Journal of Microbiology, 35 (1). pp. 21-29. DOI https://doi.org/10.1139/m89-004

Cline, Steven W and Lam, Wan L and Charlebois, Robert L and Schalkwyk, Leonard C and Doolittle, W Ford (1989) Transformation methods for halophilic archaebacteria. Canadian Journal of Microbiology, 35 (1). pp. 148-152. DOI https://doi.org/10.1139/m89-022

Hofman, Jason D and Schalkwyk, Leonard C and Doolittle, W Ford (1986) ISH51: a large, degenerate family of insertion sequence-like elements in the genome of the archaehacterium,<i>Halobacterium volcanii</i>. Nucleic Acids Research, 14 (17). pp. 6983-7000. DOI https://doi.org/10.1093/nar/14.17.6983

Conference or Workshop Item

Spiers, H and Bray, NJ and Hannon, E and Schalkwyk, LC and Wong, CC and Pidsley, R and Smith, RG and Mill, J (2015) ISDN2014_0171: Dynamic and sex‐specific changes in DNA methylation during human fetal brain development. In: UNSPECIFIED, ? - ?.

Meaburn, Emma and Harlaar, Nicole and Craig, Ian W and Schalkwyk, Leonard C and Plomin, Robert (2007) Genomewide gene expression profiles as a biological basis for non-shared environment: MZ twins discordant for reading ability. In: UNSPECIFIED, ? - ?.

D'Souza, UM and Sugden, K and Pariante, CM and Byers, H and Ward, M and Schalkwyk, LC and McGuffin, P and Aitchison, KJ (2006) Effects of antidepressant treatment on gene expression in mouse cultured cells. In: XIV World Congress on Psychiatric Genetics, 2006-10-28 - 2006-11-01, Cagliari, Italy.

Butcher, LM and Meaburn, EL and Craig, IW and Schalkwyk, LC and Plomin, R (2006) A genomewide association scan for GE interplay in childhood. In: XIV World Congress on Psychiatric Genetics, 2006-10-28 - 2006-11-01, Cagliari, Italy.

Paya-Cano, JL and Sluyter, F and Mineur, YS and Fernandes, C and Crusio, WE and Schalkwyk, LC (2006) P.1.a.015 Strain differences in susceptibility to unpredictable chronic mild stress as assessed by hippocampal gene expression profiling. In: UNSPECIFIED, ? - ?.

Binder, E and Paya-Cano, JL and Sluyter, F and Schalkwyk, LC (2006) P.1.d.016 The effects of a selective serotonin reuptake inhibitor and a tricyclic antidepressant on the behaviour of chronically stressed 129SvemJ and C57BL/6J mice in the hole board and forced swim test. In: UNSPECIFIED, ? - ?.

Huezo-Diaz, Patricia and Williamson, R and Nash, MW and Sim, SC and Alhberg, S and Hoda, F and Rietschel, M and Schmal, C and Farmer, A and Schulze, T and Hauser, J and Henigsberg, N and Maier, W and Zobel, A and Larsen, ER and Mors, O and Mendelewicz, J and Marusic, A and Perez, J and Schalkwyk, L and McGuffin, P and Craig, I and Ingelman-Sundberg, M and Aitchison, KJ (2006) CYP2D6 and CYP2C19 association data from GENDEP, a multicentre European study. In: UNSPECIFIED, ? - ?.

Meaburn, Emma and Butcher, Lee M and Harlaar, Nicole and Curtis, Charles and Craig, Ian W and Schalkwyk, Leonard C and Plomin, Robert (2006) An association scan using pooled DNA and 100k SNPS identifies a 'SNP set' for early reading. In: UNSPECIFIED, ? - ?.

Liu, L and Fernandes, C and Brookes, K and Paya-Capo, J and Asherson, P and Schalkwyk, LC (2005) P.2.07 Selecting over-active extremes in outbred heterogeneous stock (HS) mice for gene expression profiling: nominating novel candidate genes for over-activity. In: UNSPECIFIED, ? - ?.

Butcher, LM and Meaburn, E and Knight, J and Sham, PC and Schalkwyk, LC and Craig, IW and Plomin, R (2005) Allelotyping over 10,000 SNPs using DNA pools and microarrays nominates four SNPs associated with mild mental impairment. In: UNSPECIFIED, ? - ?.

Sugden, K and D'Souza, UM and McGuffin, P and Schalkwyk, LC and Aitchison, KJ and Pariante, CM (2005) Gene expression analyses of a mouse fibroblast cell line after antidepressant treatment. In: UNSPECIFIED, ? - ?.

Meaburn, EL and Butcher, LM and Knight, J and Craig, I and Schalkwyk, LC and Plomin, R (2005) QTLs for reading disability at 7 years: Genotyping pooled DNA on 100K SNP microarrays. In: UNSPECIFIED, ? - ?.

Butcher, LM and Meaburn, E and Knight, J and Sham, PC and Schalkwyk, LC and Craig, IW and Plomin, R (2005) SNPs, microarrays, and pooled DNA: Identification of four loci associated with mild mental impairment in a sample of 6000 children. In: UNSPECIFIED, ? - ?.

Fernandes, C and Liu, L and Paya-Cano, JL and Whatley, SA and Schalkwyk, LC (2004) Correlating behaviour with gene expression: Identifying genes for anxiety and cognition in the mouse. In: UNSPECIFIED, ? - ?.

Meaburn, EL and Butcher, ML and Liu, L and Fernandes, C and Sham, P and Plomin, R and Craig, I and Schalkwyk, L (2004) DNA pools on 10K genechips: Solving the QTL problem of large samples and large numbers of SNPS. In: UNSPECIFIED, ? - ?.

Tandon, K and Schalkwyk, LC and Checkley, S and Patel, M and Kinirons, M and Kerwin, RW and McGuffin, P and Aitchison, KJ (2002) CYP2D6 genotype and treatment with tricyclic antidepressants. In: X World Congress of Psychiatric Genetics, 2002-10-09 - 2002-10-13, Brussels, Belgium.

Tandon, K and Schalkwyk, L and Patel, M and Kinirons, M and Kerwin, R and McGuffin, P and Aitchison, KJ (2002) An amino acid substitution (IIe109Val) in CYP2D6. In: UNSPECIFIED, ? - ?.

DOOLITTLE, WF and CHARLEBOIS, RL and SCHALKWYK, LC and LAM, WL and CONOVER, RK and TSOULUHAS, D and CLINE, SW and HOFMAN, JD and COHEN, A (1991) PHYSICAL MAPPING AND GENE-TRANSFER METHODS FOR HALOBACTERIUM (HALOFERAX) VOLCANII. In: UNSPECIFIED, ? - ?.